Tanshinone IIA (Tan IIA) is a pharmacologically lipophilic active constituent isolated from the
roots and rhizomes of the Chinese medicinal herb Salvia miltiorrhiza Bunge (Danshen). Tan …

Significance: Targeted cancer therapy with minimal off-target consequences has shown
promise for some cancer types. Although cytochrome P450 (CYP) consists of 18 families …

Abstract Tanshinone IIA (Tan IIA), a constituent of the traditional medicinal plant Salvia
miltiorrhiza BUNGE, has been reported to possess anticancer activity through induction of …

Hepatocellular carcinoma (HCC) is one of the most lethal malignant tumours worldwide. The
mortality-to-incidence ratio is up to 91.6% in many countries, representing the third leading …

Abstract Ethnopharmacological revelvance Tanshinone IIA (TIIA) is a major component
extracted from the traditional herbal medicine salvia miltiorrhiza (Danshen), which activates …

Liver diseases are clinically common and present a substantial public health issue. Many of
the currently available drugs for the treatment of liver diseases suffer from limitations that …

What is known and objective In order to expedite the availability of drugs to treat cancers in a
cost‐effective manner, repurposing of old drugs for oncological indications is gathering …

Liver diseases cause serious public health problems because of their high global
prevalence and poor long-term clinical outcomes. With its mild and broad therapeutic …

Salvia species have been used as valuable medicinal and herbal plant in many countries.
Salvia officinalis L. and Salvia miltiorrhiza Bunge are widely used in traditional medicine for …

Increasing the drug tumor-specific accumulation and controlling their release is considered
one of the most effective ways to increase the efficacy of drugs. Here, we developed a …