Scalable manufacturing of CAR T cells for cancer immunotherapy
M Abou-el-Enein, M Elsallab, SA Feldman… - Blood cancer …, 2021 - AACR
As of April 2021, there are five commercially available chimeric antigen receptor (CAR) T
cell therapies for hematologic malignancies. With the current transition of CAR T cell …
cell therapies for hematologic malignancies. With the current transition of CAR T cell …
Microfluidic Label‐Free Hydrodynamic Separation of Blood Cells: Recent Developments and Future Perspectives
S Lee, H Kim, S Yang - Advanced Materials Technologies, 2023 - Wiley Online Library
The biophysical characteristics and counts of blood cells provide useful information
regarding pathological conditions. Therefore, the separation of blood components is a …
regarding pathological conditions. Therefore, the separation of blood components is a …
Factors affecting lymphocyte collection efficiency for the manufacture of chimeric antigen receptor T cells in adults with B‐cell malignancies
SA Tuazon, A Li, T Gooley, TW Eunson… - …, 2019 - Wiley Online Library
BACKGROUND The clinical and procedural parameters that affect the optimal collection of
lymphocytes for the production of chimeric antigen receptor (CAR) T cells remain undefined …
lymphocytes for the production of chimeric antigen receptor (CAR) T cells remain undefined …
Comparison between intermittent and continuous spectra optia leukapheresis systems for autologous peripheral blood stem cell collection
K Lisenko, P Pavel, T Bruckner… - Journal of clinical …, 2017 - Wiley Online Library
Terumo BCT recently introduced a new system for mononuclear cell (MNC) collection that
uses a Spectra Optia apheresis machine equipped with a redesigned disposable kit and …
uses a Spectra Optia apheresis machine equipped with a redesigned disposable kit and …
Evolution of MNC and lymphocyte collection settings employing different Spectra Optia® Leukapheresis systems
M Punzel, A Kozlova, A Quade, AH Schmidt… - Vox …, 2017 - Wiley Online Library
Background and Objectives The Spectra Optia® continuous mononuclear cell (CMNC
apheresis) system has emerged as the preferred device in peripheral blood stem cell …
apheresis) system has emerged as the preferred device in peripheral blood stem cell …
Current state of apheresis technology and its applications
RW Maitta - Transfusion and Apheresis Science, 2018 - Elsevier
Apheresis is at the forefront of therapeutic approaches for an increasing number of
indications caused by formation of pathologic antibodies treated by therapeutic plasma …
indications caused by formation of pathologic antibodies treated by therapeutic plasma …
[HTML][HTML] Comparison of two apheresis systems of COBE and Optia for autologous peripheral blood stem cell collection
SN Lee, JY Sohn, JH Kong, HS Eom… - Annals of Laboratory …, 2017 - ncbi.nlm.nih.gov
Peripheral blood stem cell (PBSC) transplantation following myeloablative therapy is a
mainstay of treatment for various types of malignancies. This study aimed to evaluate the …
mainstay of treatment for various types of malignancies. This study aimed to evaluate the …
Evaluating the efficiency and safety of large‐volume leukapheresis using the Spectra Optia continuous mononuclear cell collection protocol for peripheral blood stem …
Y Sumii, K Fujii, T Kondo, T Urata, M Kimura… - …, 2023 - Wiley Online Library
Background Large‐volume leukapheresis (LVL) refers to processing of more than three
volumes of blood in a single session for peripheral blood stem cell collection. Recently …
volumes of blood in a single session for peripheral blood stem cell collection. Recently …
Advances in biomarker detection: Alternative approaches for blood-based biomarker detection
M Rosado, R Silva, MG Bexiga, JG Jones… - Advances in clinical …, 2019 - Elsevier
In the clinical setting, a blood sample is typically the starting point for biomarker search and
discovery. Mass spectrometry (MS) is a highly sensitive and informative method for …
discovery. Mass spectrometry (MS) is a highly sensitive and informative method for …
Impact of mobilization strategies on peripheral blood stem cell collection efficiency and product quality: a retrospective single-center study
P Rajsp, M Branka, N Besson, A Tanzmann, N Worel - Cancers, 2022 - mdpi.com
Simple Summary We retrospectively reviewed data from cancer patients undergoing
peripheral blood stem cell (PBSC) collection following different mobilization regimens (with …
peripheral blood stem cell (PBSC) collection following different mobilization regimens (with …