Angiogenesis and lymphangiogenesis often occur in response to tissue injury or in the
presence of pathology (eg, cancer), and it is these types of environments in which …

Autotaxin (ATX) is a member of the nucleotide pyrophosphatase/phosphodiesterase family
of ectoenzymes that hydrolyzes phosphodiester bonds of various nucleotides. It possesses …

Rationale: Myocardial infarction (MI) is one of the most dangerous adverse cardiovascular
events. Our previous study found that lysophosphatidic acid (LPA) is increased in human …

Lysophosphatidic acid (LPA) is a potent lipid mediator with a wide variety of biological
actions mediated through G protein-coupled receptors (LPA1-6). LPA4 has been identified …

The lymphatic system plays a significant role in homeostasis and drainage of excess fluid
back into venous circulation. Lymphatics are also associated with a number of diseases …

Lysophosphatidic acid (LPA) is a well-characterized bioactive lipid mediator, which is
involved in development, physiology, and pathological processes of the cardiovascular …

A hallmark of G-protein-coupled receptors (GPCRs) is their ability to recognize and respond
to chemically diverse ligands. Lysophospholipids constitute a relatively recent addition to …

Objective Lymphatic and blood microvascular systems are critical for tissue function. Insights
into the coordination of both systems can be gained by investigating the relationships …

Endometriosis is an angiogenesis-dependent disease. Many studies demonstrated
inhibition of angiogenesis leads to inhibition of endometriotic growth, however underlying …

Lysophosphatidic acid (LPA), a member of the phospholipid autacoid family, is present in
human follicular fluid. The aim of the present study was to compare the developmental …