Tracing the peopling of the world through genomics
Advances in the sequencing and the analysis of the genomes of both modern and ancient
peoples have facilitated a number of breakthroughs in our understanding of human …
peoples have facilitated a number of breakthroughs in our understanding of human …
African genetic diversity: implications for human demographic history, modern human origins, and complex disease mapping
MC Campbell, SA Tishkoff - Annu. Rev. Genomics Hum. Genet., 2008 - annualreviews.org
Comparative studies of ethnically diverse human populations, particularly in Africa, are
important for reconstructing human evolutionary history and for understanding the genetic …
important for reconstructing human evolutionary history and for understanding the genetic …
Southern African ancient genomes estimate modern human divergence to 350,000 to 260,000 years ago
Southern Africa is consistently placed as a potential region for the evolution of Homo
sapiens. We present genome sequences, up to 13x coverage, from seven ancient …
sapiens. We present genome sequences, up to 13x coverage, from seven ancient …
Ancient DNA and deep population structure in sub-Saharan African foragers
Multiple lines of genetic and archaeological evidence suggest that there were major
demographic changes in the terminal Late Pleistocene epoch and early Holocene epoch of …
demographic changes in the terminal Late Pleistocene epoch and early Holocene epoch of …
The genetic structure and history of Africans and African Americans
SA Tishkoff, FA Reed, FR Friedlaender, C Ehret… - science, 2009 - science.org
Africa is the source of all modern humans, but characterization of genetic variation and of
relationships among populations across the continent has been enigmatic. We studied 121 …
relationships among populations across the continent has been enigmatic. We studied 121 …
Age of the Association between Helicobacter pylori and Man
When modern humans left Africa ca. 60,000 years ago (60 kya), they were already infected
with Helicobacter pylori, and these bacteria have subsequently diversified in parallel with …
with Helicobacter pylori, and these bacteria have subsequently diversified in parallel with …
Hunter-gatherer genomic diversity suggests a southern African origin for modern humans
BM Henn, CR Gignoux, M Jobin… - Proceedings of the …, 2011 - National Acad Sciences
Africa is inferred to be the continent of origin for all modern human populations, but the
details of human prehistory and evolution in Africa remain largely obscure owing to the …
details of human prehistory and evolution in Africa remain largely obscure owing to the …
Genomic variation in seven Khoe-San groups reveals adaptation and complex African history
The history of click-speaking Khoe-San, and African populations in general, remains poorly
understood. We genotyped∼ 2.3 million single-nucleotide polymorphisms in 220 southern …
understood. We genotyped∼ 2.3 million single-nucleotide polymorphisms in 220 southern …
Dating genomic variants and shared ancestry in population-scale sequencing data
The origin and fate of new mutations within species is the fundamental process underlying
evolution. However, while much attention has been focused on characterizing the presence …
evolution. However, while much attention has been focused on characterizing the presence …
Ages for the Middle Stone Age of southern Africa: implications for human behavior and dispersal
The expansion of modern human populations in Africa 80,000 to 60,000 years ago and their
initial exodus out of Africa have been tentatively linked to two phases of technological and …
initial exodus out of Africa have been tentatively linked to two phases of technological and …