Plant‐derived lectins as potential cancer therapeutics and diagnostic tools
M Mazalovska, JC Kouokam - BioMed Research International, 2020 - Wiley Online Library
Cancer remains a global health challenge, with high morbidity and mortality, despite the
recent advances in diagnosis and treatment. Multiple compounds assessed as novel …
recent advances in diagnosis and treatment. Multiple compounds assessed as novel …
Overview of the structure–function relationships of mannose-specific lectins from plants, algae and fungi
A Barre, Y Bourne, EJM Van Damme… - International journal of …, 2019 - mdpi.com
To date, a number of mannose-binding lectins have been isolated and characterized from
plants and fungi. These proteins are composed of different structural scaffold structures …
plants and fungi. These proteins are composed of different structural scaffold structures …
ConA-like lectins: high similarity proteins as models to study structure/biological activities relationships
BS Cavada, VR Pinto-Junior, VJS Osterne… - International journal of …, 2018 - mdpi.com
Lectins are a widely studied group of proteins capable of specific and reversible binding to
carbohydrates. Undoubtedly, the best characterized are those extracted from plants of the …
carbohydrates. Undoubtedly, the best characterized are those extracted from plants of the …
[HTML][HTML] ConBr lectin modulates MAPKs and Akt pathways and triggers autophagic glioma cell death by a mechanism dependent upon caspase-8 activation
IAV Wolin, IA Heinrich, APM Nascimento, PG Welter… - Biochimie, 2021 - Elsevier
Glioblastoma multiforme is the most aggressive type of glioma, with limited treatment and
poor prognosis. Despite some advances over the last decade, validation of novel and …
poor prognosis. Despite some advances over the last decade, validation of novel and …
Proteins and their functionalization for finding therapeutic avenues in cancer: Current status and future prospective
Despite the remarkable advancement in the health care sector, cancer remains the second
most fatal disease globally. The existing conventional cancer treatments primarily include …
most fatal disease globally. The existing conventional cancer treatments primarily include …
[HTML][HTML] Anti-glioma properties of DVL, a lectin purified from Dioclea violacea
APM Nascimento, JL Knaut, DK Rieger… - International journal of …, 2018 - Elsevier
Plant lectins have been studied owing to their structural properties and biological effects that
include agglutinating activity, antidepressant-like effect and antitumor property. The results …
include agglutinating activity, antidepressant-like effect and antitumor property. The results …
[HTML][HTML] Insights into anti-pathogenic activities of mannose lectins
PM dos Santos Silva, WF de Oliveira… - International journal of …, 2019 - Elsevier
Carbohydrate-binding proteins, also known as lectins, are valuable tools for biotechnology,
including pharmacological uses. Mannose lectins obtained from plant and animal sources …
including pharmacological uses. Mannose lectins obtained from plant and animal sources …
[HTML][HTML] Lectin from Dioclea violacea induces autophagy in U87 glioma cells
APM Nascimento, IAV Wolin, PG Welter… - International journal of …, 2019 - Elsevier
The antitumor activity of DVL, a lectin purified from Dioclea violacea seeds, on the U87
human glioma cell line was evaluated and compared with Canavalia ensiformis lectin …
human glioma cell line was evaluated and compared with Canavalia ensiformis lectin …
Omics-driven bioinformatics for plant lectins discovery and functional annotation–A comprehensive review
RCC da Silva, RS Roldan-Filho… - International Journal of …, 2024 - Elsevier
Lectins are known for their specific and reversible binding capacity to carbohydrates. These
molecules have been particularly explored in plants due to their reported properties …
molecules have been particularly explored in plants due to their reported properties …
[HTML][HTML] Comprehensive review on Caelsalpinioideae lectins: From purification to biological activities
BS Cavada, VR Pinto-Junior, VJS Osterne… - International Journal of …, 2020 - Elsevier
Lectins are a class of proteins with specific and reversible carbohydrate binding properties.
Plant lectins constitute the group of these proteins most studied, placing emphasis on the …
Plant lectins constitute the group of these proteins most studied, placing emphasis on the …