Non-targeted metabolomics is the hypothesis generating, global unbiased analysis of all the
small-molecule metabolites present within a biological system, under a given set of …

Dysbiosis of the gut microbiome is associated with host health conditions. Many diseases
have shown to have correlations with imbalanced microbiota, including obesity …

Metabolic reprogramming is a hallmark of cancer. However, systematic characterizations of
metabolites in triple-negative breast cancer (TNBC) are still lacking. Our study profiled the …

Metabolomics holds the promise as a new technology to diagnose highly heterogeneous
diseases. Conventionally, metabolomics data analysis for diagnosis is done using various …

Increased glutamine metabolism (glutaminolysis) is a hallmark of cancer and is recognised
as a key metabolic change in cancer cells. Breast cancer is a heterogeneous disease with …

The interaction between features can provide essential information that affects the
performances of learning models. Nevertheless, most feature selection methods do not take …

Tumor subtype-specific metabolic reprogrammers could serve as targets of therapeutic
intervention. Here we show that triple-negative breast cancer (TNBC) exhibits a hyper …

Tumor cells display fundamental changes in metabolism and nutrient uptake in order to
utilize additional nutrient sources to meet their enhanced bioenergetic requirements …

Most cancers are lethal and metabolic alterations are considered a hallmark of this deadly
disease. Genomics and proteomics have contributed vastly to understand cancer biology …

Estrogens and estrogen receptors (ERs) regulate metabolism in both normal physiology and
in disease. The metabolic characteristics of intrinsic breast cancer subtypes change based …