Glioblastoma (GBM) is the most prevalent and lethal adult primary central nervous system
cancer. An immunosuppresive and highly heterogeneous tumor microenvironment …

Tumorigenesis is closely related to the loss of control of many genes. Urokinase-type
plasminogen activator receptor (uPAR), a glycolipid-anchored protein on the cell surface, is …

Bloodstream infection is a major public health concern associated with high mortality and
high healthcare costs worldwide. Bacteremia can trigger fatal sepsis whose prevention …

During ageing, the glomerular and tubular basement membranes (BM) of the kidney
undergo a progressive decline in function that is underpinned by histological changes …

Biomaterial surface chemistry engenders profound consequences on cell adhesion and the
ultimate tissue response by adsorbing proteins from extracellular matrix, where vitronectin …

Pathogens that colonize deep tissues and spread systemically encounter the innate host
resistance mechanism of complement‐mediated lysis and complement opsonization leading …

The human blood protein vitronectin (Vn) is a major component of the abnormal deposits
associated with age-related macular degeneration, Alzheimer's disease, and many other …

The low sensitivity of nuclear magnetic resonance (NMR) is a major bottleneck for studying
biomolecular structures of complex biomolecular assemblies. Cryogenically cooled probe …

Many of the diseases that plague society today are driven by a loss of protein quality. One
method to quantify protein quality is to measure the protein folding stability (PFS). Here, we …

Ail is shown to be an essential virulence factor with multiple roles in pathogenesis. The
recent adaptation of Yersinia pestis to high virulence, which included genomic reduction to …