BNP and NT-proBNP as diagnostic biomarkers for cardiac dysfunction in both clinical and forensic medicine

Z Cao, Y Jia, B Zhu - International journal of molecular sciences, 2019 - mdpi.com
Currently, brain natriuretic peptide (BNP) and N-terminal proBNP (NT-proBNP) are widely
used as diagnostic biomarkers for heart failure (HF) and cardiac dysfunction in clinical …

Neutral endopeptidase inhibition and the natriuretic peptide system: an evolving strategy in cardiovascular therapeutics

S Mangiafico, LC Costello-Boerrigter… - European heart …, 2013 - academic.oup.com
Hypertension and heart failure (HF) are common diseases that, despite advances in medical
therapy, continue to be associated with high morbidity and mortality. Therefore, innovative …

Heart failure, chronic diuretic use, and increase in mortality and hospitalization: an observational study using propensity score methods

A Ahmed, A Husain, TE Love, G Gambassi… - European heart …, 2006 - academic.oup.com
Aims Non-potassium-sparing diuretics are commonly used in heart failure (HF). They
activate the neurohormonal system, and are potentially harmful. Yet, the long-term effects of …

Role of diminished renal function in cardiovascular mortality: marker or pathogenetic factor?

RW Schrier - Journal of the American College of Cardiology, 2006 - jacc.org
Role of Diminished Renal Function in Cardiovascular Mortality: Marker or Pathogenetic
Factor? Robert W. Schrier The interactions between the heart and the kidney recently have …

Pharmacological characterization of the diuretic effect of Hibiscus sabdariffa Linn (Malvaceae) extract

J Alarcón-Alonso, A Zamilpa, FA Aguilar… - Journal of …, 2012 - Elsevier
ETHNOPHARMACOLOGICAL RELEVANCE: Hibiscus sabdariffa L.(Malvaceae) populary
known in Mexico as “Jamaica”,“flor de Jamaica”, has widely used in Mexican Traditional …

The natriuretic peptides in cardiovascular medicine

VK Munagala, JC Burnett Jr, MM Redfield - Current problems in cardiology, 2004 - Elsevier
Within the last five years, assay systems for measurement of plasma levels of brain
natriuretic peptide (BNP) have been approved as a diagnostic aid for heart failure (HF) …

BNP as a major player in the heart-kidney connection

R Okamoto, Y Ali, R Hashizume, N Suzuki… - International journal of …, 2019 - mdpi.com
Brain natriuretic peptide (BNP) is an important biomarker for patients with heart failure,
hypertension and cardiac hypertrophy. Although it is known that BNP levels are relatively …

Natriuretic peptides and therapeutic applications

CYW Lee, JC Burnett - Heart failure reviews, 2007 - Springer
Since the discovery of atrial natriuretic factor by de Bold et al., there has been tremendous
progress in our understanding of the physiologic, diagnostic and therapeutic roles of the …

Decongestion strategies and renin-angiotensin-aldosterone system activation in acute heart failure

RJ Mentz, SR Stevens, AD DeVore, A Lala, JM Vader… - JACC: Heart Failure, 2015 - jacc.org
Objectives: The purpose of this study was to assess the relationship between biomarkers of
renin-angiotensin-aldosterone system (RAAS) activation and decongestion strategies …

Nesiritide does not improve renal function in patients with chronic heart failure and worsening serum creatinine

DJ Wang, TC Dowling, D Meadows, T Ayala… - Circulation, 2004 - Am Heart Assoc
Background—Nesiritide (synthetic human brain natriuretic peptide) is approved for the
treatment of symptomatic heart failure. However, studies of brain natriuretic peptide in …