Translational applications of hydrogels

S Correa, AK Grosskopf, H Lopez Hernandez… - Chemical …, 2021 - ACS Publications
Advances in hydrogel technology have unlocked unique and valuable capabilities that are
being applied to a diverse set of translational applications. Hydrogels perform functions …

[HTML][HTML] Supramolecular engineering of hydrogels for drug delivery

S Bernhard, MW Tibbitt - Advanced Drug Delivery Reviews, 2021 - Elsevier
Supramolecular binding motifs are increasingly employed in the design of biomaterials. The
ability to rationally engineer specific yet reversible associations into polymer networks with …

Smart injectable hydrogels for cancer immunotherapy

Y Chao, Q Chen, Z Liu - Advanced Functional Materials, 2020 - Wiley Online Library
Hydrogels, a class of materials with a 3D network structure, are widely used in various fields
especially in biomedicine. Injectable hydrogels could facilitate the encapsulation and …

A review on biomedical application of polysaccharide-based hydrogels with a focus on drug delivery systems

B Farasati Far, MR Naimi-Jamal, M Safaei, K Zarei… - Polymers, 2022 - mdpi.com
Over the last years of research on drug delivery systems (DDSs), natural polymer-based
hydrogels have shown many scientific advances due to their intrinsic properties and a wide …

Co-delivery of chemotherapeutics and proteins for synergistic therapy

C He, Z Tang, H Tian, X Chen - Advanced drug delivery reviews, 2016 - Elsevier
Combination therapy with chemotherapeutics and protein therapeutics, typically cytokines
and antibodies, has been a type of crucial approaches for synergistic cancer treatment …

Heparin-based and heparin-inspired hydrogels: size-effect, gelation and biomedical applications

C He, H Ji, Y Qian, Q Wang, X Liu, W Zhao… - Journal of Materials …, 2019 - pubs.rsc.org
Heparin is the highest negatively charged biomolecule, which is a polysaccharide belonging
to the glycosaminoglycan family, and its role as a regulator of various proteins, cells and …

Supramolecular cyclodextrin-based drug nanocarriers

SMN Simões, A Rey-Rico, A Concheiro… - Chemical …, 2015 - pubs.rsc.org
Supramolecular systems formed by the binding of several cyclodextrins (CDs) to polymers or
lipids, either via non-covalent or covalent links, open a wide range of possibilities for the …

Fabrication of a micellar supramolecular hydrogel for ocular drug delivery

Z Zhang, Z He, R Liang, Y Ma, W Huang… - …, 2016 - ACS Publications
In this paper, we describe a simple method for constructing a micellar supramolecular
hydrogel, composed of a low-molecular-weight methoxy poly (ethylene glycol)(M n= 2000 …

A star-shaped porphyrin-arginine functionalized poly (L-lysine) copolymer for photo-enhanced drug and gene co-delivery

D Ma, QM Lin, LM Zhang, YY Liang, W Xue - Biomaterials, 2014 - Elsevier
The co-delivery of drug and gene has become the primary strategy in cancer and other
disease therapy. To co-deliver hydrophobic drug and functional gene efficiently into tumor …

Injectable magnetic supramolecular hydrogel with magnetocaloric liquid-conformal property prevents post-operative recurrence in a breast cancer model

H Wu, L Song, L Chen, W Zhang, Y Chen, F Zang… - Acta biomaterialia, 2018 - Elsevier
Locoregional recurrence of breast cancer after tumor resection represents several clinical
challenges. Here, we demonstrate that co-delivery of chemotherapy and thermotherapeutic …