Modeling hypothalamic pathophysiology in vitro for metabolic, circadian, and sleep disorders
H Leal, C Carvalhas-Almeida, AR Álvaro… - Trends in Endocrinology …, 2024 - cell.com
The hypothalamus, a small and intricate brain structure, orchestrates numerous
neuroendocrine functions through specialized neurons and nuclei. Disruption of this …
neuroendocrine functions through specialized neurons and nuclei. Disruption of this …
[HTML][HTML] Morphogenetic Designs, and Disease Models in Central Nervous System Organoids
M Bock, SJ Hong, S Zhang, Y Yu, S Lee… - … Journal of Molecular …, 2024 - ncbi.nlm.nih.gov
Since the emergence of the first cerebral organoid (CO) in 2013, advancements have
transformed central nervous system (CNS) research. Initial efforts focused on studying the …
transformed central nervous system (CNS) research. Initial efforts focused on studying the …
[HTML][HTML] The application of brain organoid for drug discovery in mitochondrial diseases
KX Liang - The International Journal of Biochemistry & Cell …, 2024 - Elsevier
Mitochondrial diseases are difficult to treat due to the complexity and multifaceted nature of
mitochondrial dysfunction. Brain organoids are three-dimensional (3D) structures derived …
mitochondrial dysfunction. Brain organoids are three-dimensional (3D) structures derived …
Neuron-Astrocyte Interactions: A Human Perspective
T Pio, EJ Hill, N Kebede, J Andersen… - … -Neuron Interactions in …, 2024 - Springer
This chapter explores the intricate interactions between neurons and astrocytes within the
nervous system with a particular emphasis on studies conducted in human tissue or with …
nervous system with a particular emphasis on studies conducted in human tissue or with …