[HTML][HTML] Network pharmacology databases for traditional Chinese medicine: review and assessment
The research field of systems biology has greatly advanced and, as a result, the concept of
network pharmacology has been developed. This advancement, in turn, has shifted the …
network pharmacology has been developed. This advancement, in turn, has shifted the …
Polypharmacology: drug discovery for the future
AS Reddy, S Zhang - Expert review of clinical pharmacology, 2013 - Taylor & Francis
In recent years, even with remarkable scientific advancements and a significant increase of
global research and development spending, drugs are frequently withdrawn from markets …
global research and development spending, drugs are frequently withdrawn from markets …
Comparative toxicogenomics database (CTD): update 2021
AP Davis, CJ Grondin, RJ Johnson… - Nucleic acids …, 2021 - academic.oup.com
Abstract The public Comparative Toxicogenomics Database (CTD; http://ctdbase. org/) is an
innovative digital ecosystem that relates toxicological information for chemicals, genes …
innovative digital ecosystem that relates toxicological information for chemicals, genes …
The comparative toxicogenomics database: update 2019
AP Davis, CJ Grondin, RJ Johnson… - Nucleic acids …, 2019 - academic.oup.com
Abstract The Comparative Toxicogenomics Database (CTD; http://ctdbase. org/) is a premier
public resource for literature-based, manually curated associations between chemicals …
public resource for literature-based, manually curated associations between chemicals …
The comparative toxicogenomics database: update 2017
AP Davis, CJ Grondin, RJ Johnson… - Nucleic acids …, 2017 - academic.oup.com
Abstract The Comparative Toxicogenomics Database (CTD; http://ctdbase. org/) provides
information about interactions between chemicals and gene products, and their …
information about interactions between chemicals and gene products, and their …
[HTML][HTML] Target identification among known drugs by deep learning from heterogeneous networks
Without foreknowledge of the complete drug target information, development of promising
and affordable approaches for effective treatment of human diseases is challenging. Here …
and affordable approaches for effective treatment of human diseases is challenging. Here …
The Comparative Toxicogenomics Database's 10th year anniversary: update 2015
AP Davis, CJ Grondin, K Lennon-Hopkins… - Nucleic acids …, 2015 - academic.oup.com
Ten years ago, the Comparative Toxicogenomics Database (CTD; http://ctdbase. org/) was
developed out of a need to formalize, harmonize and centralize the information on …
developed out of a need to formalize, harmonize and centralize the information on …
Advancing computational toxicology in the big data era by artificial intelligence: data-driven and mechanism-driven modeling for chemical toxicity
HL Ciallella, H Zhu - Chemical research in toxicology, 2019 - ACS Publications
In 2016, the Frank R. Lautenberg Chemical Safety for the 21st Century Act became the first
US legislation to advance chemical safety evaluations by utilizing novel testing approaches …
US legislation to advance chemical safety evaluations by utilizing novel testing approaches …
Machine learning-based prediction of drug–drug interactions by integrating drug phenotypic, therapeutic, chemical, and genomic properties
Abstract Objective Drug–drug interactions (DDIs) are an important consideration in both
drug development and clinical application, especially for co-administered medications …
drug development and clinical application, especially for co-administered medications …
The comparative toxicogenomics database: update 2013
AP Davis, CG Murphy, R Johnson, JM Lay… - Nucleic acids …, 2013 - academic.oup.com
Abstract The Comparative Toxicogenomics Database (CTD; http://ctdbase. org/) provides
information about interactions between environmental chemicals and gene products and …
information about interactions between environmental chemicals and gene products and …