Effect of aberrant DNA methylation on cancer stem cell properties
DNA methylation, as an epigenetic mechanism, occurs by adding a methyl group of
cytosines in position 5 by DNA methyltransferases and has essential roles in cellular …
cytosines in position 5 by DNA methyltransferases and has essential roles in cellular …
Clonal selection parallels between normal and cancer tissues
Clonal selection and drift drive both normal tissue and cancer development. However, the
biological mechanisms and environmental conditions underpinning these processes remain …
biological mechanisms and environmental conditions underpinning these processes remain …
Down syndrome altered cell composition in blood, brain, and buccal swab samples profiled by DNA-methylation-based cell-type deconvolution
Down syndrome (DS) is a genetic disorder caused by an extra copy of chromosome 21 that
presents developmental dysfunction and intellectual disability. To better understand the …
presents developmental dysfunction and intellectual disability. To better understand the …
Integrative Pan-Cancer Analysis Reveals Decreased Melatonergic Gene Expression in Carcinogenesis and RORA as a Prognostic Marker for Hepatocellular …
Y Zou, H Sun, Y Guo, Y Shi, Z Jiang, J Huang… - Frontiers in …, 2021 - frontiersin.org
Background Melatonin has been shown to play a protective role in the development and
progression of cancer. However, the relationship between alterations in the melatonergic …
progression of cancer. However, the relationship between alterations in the melatonergic …
Biophysical modeling of the ionizing radiation influence on cells using the stochastic (Monte Carlo) and deterministic (analytical) approaches
KW Fornalski, Ł Adamowski, E Bugała… - Dose …, 2022 - journals.sagepub.com
This review article describes our simplified biophysical model for the response of a group of
cells to ionizing radiation. The model, which is a product of 10 years of studies, acts as (a) a …
cells to ionizing radiation. The model, which is a product of 10 years of studies, acts as (a) a …
[PDF][PDF] Biophysical Modeling of the Ionizing Radiation Influence on Cells Using the Stochastic (Monte Carlo) and Deterministic (Analytical) Approaches
M Kirejczyk, J Kopycinski, J Krasowska, P Kukulski… - 2022 - academia.edu
This review article describes our simplified biophysical model for the response of a group of
cells to ionizing radiation. The model, which is a product of 10 years of studies, acts as (a) a …
cells to ionizing radiation. The model, which is a product of 10 years of studies, acts as (a) a …
Identification of a foetal epigenetic compartment in adult human kidney
The mammalian kidney has extensive repair capacity; however, identifying adult renal stem
cells has proven elusive. We applied an epigenetic marker of foetal cell origin (FCO) in …
cells has proven elusive. We applied an epigenetic marker of foetal cell origin (FCO) in …
Identification of a foetal epigenetic compartment in adult human kidney
The mammalian kidney has extensive repair capacity; however, identifying adult renal stem
cells has proven elusive. We applied an epigenetic marker of foetal cell origin (FCO) in …
cells has proven elusive. We applied an epigenetic marker of foetal cell origin (FCO) in …