[HTML][HTML] Cognitive impact of COVID-19: looking beyond the short term

S Miners, PG Kehoe, S Love - Alzheimer's research & therapy, 2020 - Springer
COVID-19 is primarily a respiratory disease but up to two thirds of hospitalised patients show
evidence of central nervous system (CNS) damage, predominantly ischaemic, in some …

[HTML][HTML] Hyperactivation of P2X7 receptors as a culprit of COVID-19 neuropathology

DE Ribeiro, A Oliveira-Giacomelli, T Glaser… - Molecular …, 2021 - nature.com
Scientists and health professionals are exhaustively trying to contain the coronavirus
disease 2019 (COVID-19) pandemic by elucidating viral invasion mechanisms, possible …

[HTML][HTML] ACE2 activation protects against cognitive decline and reduces amyloid pathology in the Tg2576 mouse model of Alzheimer's disease

CE Evans, JS Miners, G Piva, CL Willis, DM Heard… - Acta …, 2020 - Springer
Mid-life hypertension and cerebrovascular dysfunction are associated with increased risk of
later life dementia, including Alzheimer's disease (AD). The classical renin–angiotensin …

Endothelial dysfunction in the brain: setting the stage for stroke and other cerebrovascular complications of COVID-19

M Sashindranath, HH Nandurkar - Stroke, 2021 - Am Heart Assoc
The Coronavirus disease 2019 (COVID)-19 pandemic has already affected millions
worldwide, with a current mortality rate of 2.2%. While it is well-established that severe acute …

International Union of Basic and Clinical Pharmacology. XCIX. Angiotensin receptors: interpreters of pathophysiological angiotensinergic stimuli

SS Karnik, H Unal, JR Kemp, KC Tirupula… - Pharmacological …, 2015 - ASPET
The renin angiotensin system (RAS) produced hormone peptides regulate many vital body
functions. Dysfunctional signaling by receptors for RAS peptides leads to pathologic states …

[HTML][HTML] Global prevalence of prolonged gastrointestinal symptoms in COVID-19 survivors and potential pathogenesis: A systematic review and meta-analysis

F Yusuf, M Fahriani, SS Mamada, A Frediansyah… - …, 2021 - ncbi.nlm.nih.gov
Background: This study aimed to determine the cumulative prevalence of prolonged
gastrointestinal (GI) symptoms, including nausea, vomiting, diarrhea, lack of appetite …

Mas and its related G protein–coupled receptors, Mrgprs

M Bader, N Alenina, MA Andrade-Navarro… - Pharmacological …, 2014 - ASPET
The Mas-related G protein–coupled receptors (Mrgprs or Mas-related genes) comprise a
subfamily of receptors named after the first discovered member, Mas. For most Mrgprs …

[HTML][HTML] Brain renin–angiotensin system as novel and potential therapeutic target for Alzheimer's disease

R Loera-Valencia, F Eroli, S Garcia-Ptacek… - International journal of …, 2021 - mdpi.com
The activation of the brain renin-angiotensin system (RAS) plays a pivotal role in the
pathophysiology of cognition. While the brain RAS has been studied before in the context of …

[HTML][HTML] Hemorrhagic and ischemic stroke in patients with coronavirus disease 2019: incidence, risk factors, and pathogenesis-a systematic review and meta-analysis

S Syahrul, HA Maliga, M Ilmawan, M Fahriani… - …, 2021 - ncbi.nlm.nih.gov
Background: In this study, we aimed to determine the global prevalence, chronological order
of symptom appearance, and mortality rates with regard to hemorrhagic and ischemic stroke …

[HTML][HTML] Blood pressure and penumbral sustenance in stroke from large vessel occlusion

RW Regenhardt, AS Das, CJ Stapleton… - Frontiers in …, 2017 - frontiersin.org
The global burden of stroke remains high, and of the various subtypes of stroke, large vessel
occlusions (LVOs) account for the largest proportion of stroke-related death and disability …