Indoloquinolines as scaffolds for drug discovery
J Lavrado, R Moreira, A Paulo - Current medicinal chemistry, 2010 - ingentaconnect.com
Traditional medicines have contributed greatly over the centuries to the discovery and
development of new therapeutic agents and indoloquinoline alkaloids may represent a new …
development of new therapeutic agents and indoloquinoline alkaloids may represent a new …
[HTML][HTML] Advancements in the synthesis of fused tetracyclic quinoline derivatives
RA Mekheimer, MA Al-Sheikh, HY Medrasi… - RSC advances, 2020 - pubs.rsc.org
Fused tetracyclic systems containing a quinoline nucleus represent an important class of
heterocyclic bioactive natural products and pharmaceuticals because of their significant and …
heterocyclic bioactive natural products and pharmaceuticals because of their significant and …
Synthesis and evaluation of quindoline derivatives as G-quadruplex inducing and stabilizing ligands and potential inhibitors of telomerase
JL Zhou, YJ Lu, TM Ou, JM Zhou… - Journal of medicinal …, 2005 - ACS Publications
A new series of quindoline derivatives (4a− j) were designed and synthesized to develop
novel and potent telomerase inhibitors. The interaction of the G-quadruplex of human …
novel and potent telomerase inhibitors. The interaction of the G-quadruplex of human …
Isolation, biological activities and synthesis of indoloquinoline alkaloids: cryptolepine, isocryptolepine and neocryptolepine
P T. Parvatkar, P S. Parameswaran… - Current Organic …, 2011 - benthamdirect.com
The tetracyclic heteroaromatic compounds cryptolepine, isocryptolepine and
neocryptolepine are all naturally occurring indoloquinoline alkaloids isolated from the shrub …
neocryptolepine are all naturally occurring indoloquinoline alkaloids isolated from the shrub …
Indolo [3, 2-b] quinolines: synthesis, biological evaluation and structure activity-relationships
EVK Suresh Kumar, JR Etukala… - Mini reviews in …, 2008 - ingentaconnect.com
The tetracyclic indolo [3, 2-b] quinoline ring system constitutes an important structural moiety
in natural products exhibiting numerous biological activities. In particular, indolo [3, 2-b] …
in natural products exhibiting numerous biological activities. In particular, indolo [3, 2-b] …
The chemistry of the triazolopyridines: an update
G Jones - 2002 - Elsevier
The Chemistry of the Triazolopyridines: an Update Page 1 ADVANCES IN HETEROCYCLIC
CHEMISTRY, VOL. 83 The Chemistry of the Triazolopyridines: an Update GURNOS JONES …
CHEMISTRY, VOL. 83 The Chemistry of the Triazolopyridines: an Update GURNOS JONES …
Substituted indoloquinolines as new antifungal agents
SY Ablordeppey, P Fan, S Li, AM Clark… - Bioorganic & medicinal …, 2002 - Elsevier
Cryptolepine (2) possesses desirable properties to serve as a lead in developing new
antifungal agents. Using SAR techniques, several analogues of cryptolepine were designed …
antifungal agents. Using SAR techniques, several analogues of cryptolepine were designed …
Synthesis of thieno-fused five-and six-membered nitrogen and oxygen heterocycles via intramolecular heteroannulation of 4, 5-substituted 3-amino or 3-hydroxy 2 …
A Acharya, V Gautam, H Ila - The Journal of Organic Chemistry, 2017 - ACS Publications
Diverse general high-yield routes for novel thieno-fused five-and six-membered nitrogen
and oxygen heterocycles such as thieno [3, 2-b] pyrroles, thieno [3, 2-b] furans, thieno [3, 2 …
and oxygen heterocycles such as thieno [3, 2-b] pyrroles, thieno [3, 2-b] furans, thieno [3, 2 …
Methods of synthesis of natural indoloquinolines isolated from Cryptolepis sanguinolenta
ON Nadein, DА Aksenov, GM Abakarov… - Chemistry of …, 2019 - Springer
The review summarizes the approaches to the synthesis of natural biologically active
indoloquinoline systems isolated from Cryptolepis sanguinolenta published over the past …
indoloquinoline systems isolated from Cryptolepis sanguinolenta published over the past …
Synthesis and evaluation of isosteres of N-methyl indolo [3, 2-b]-quinoline (cryptolepine) as new antiinfective agents
XY Zhu, LG Mardenborough, S Li, A Khan… - Bioorganic & medicinal …, 2007 - Elsevier
Isosteres of cryptolepine (1) were synthesized and evaluated for their antiinfective activities.
Overall, the sulfur isostere, 5-methyl benzothieno [3, 2-b] quinolinium salt (5b), was …
Overall, the sulfur isostere, 5-methyl benzothieno [3, 2-b] quinolinium salt (5b), was …