Highly sophisticated mechanisms that modulate protein structure and function, which involve
synthesis and degradation, have evolved to maintain cellular homeostasis. Perturbations in …

Yin Yang 1 (YY1), a dual function transcription factor, is known to regulate transcriptional
activation and repression of many genes associated with multiple cellular processes …

Tumorigenesis is a multistep process characterized by the acquisition of genetic and
epigenetic alterations. During the course of malignancy development, tumor cells acquire …

MITF governs multiple steps in the development of melanocytes, including specification from
neural crest, growth, survival, and terminal differentiation. In addition, the level of MITF …

Abstract Background Yin Yang‐1 (YY1) is identified as a transcription factor with multiple
functions. However, the role of YY1 in tumorigenesis remains controversial and its regulatory …

Transcription enhancers are essential activators of V (D) J recombination that orchestrate
non-coding transcription through complementary, unrearranged gene segments. How …

Classical zinc fingers (ZFs) are traditionally considered to act as sequence-specific DNA-
binding domains. More recently, classical ZFs have been recognised as potential RNA …

YY1 is a ubiquitously expressed, intrinsically disordered transcription factor involved in
neural development. The oligomeric state of YY1 varies depending on the environment …

The recent progressive increase in the incidence of invasive fungal infections, especially in
immunocompromised patients, makes the search for new therapies crucial in the face of the …

Hepatocellular carcinoma (HCC) is a common digestive tumor with high fatality worldwide.
Previous studies have shown that Reticulocalbin-2 (RCN2) was a crucial factor for HCC …