Kaposi's sarcoma had been recognized as unique human cancer for a century before it
manifested as an AIDS-defining illness with a suspected infectious etiology. The discovery of …

Viruses are obligate intracellular pathogens whose biological success depends upon
replication and packaging of viral genomes, and transmission of progeny viruses to new …

An important step in the herpesvirus life cycle is the switch from latency to lytic reactivation.
In order to study the life cycle of Kaposi's sarcoma-associated herpesvirus (KSHV), we …

Although the Janus kinase-signal transducer and activator of transcription (JAK-STAT)
signaling pathway is part of the antiviral response in arthropods such as Drosophila, here …

The Kaposi's sarcoma-associated herpesvirus (KSHV) genome consists of an approximately
140-kb unique coding region flanked by 30–40 copies of a 0.8-kb terminal repeat (TR) …

Human immunodeficiency virus type 1 (HIV-1) infection significantly increases the risk of
Kaposi's sarcoma (KS) occurrence in individuals infected with Kaposi's sarcoma-associated …

White spot syndrome virus (WSSV) is a serious epidemic pathogen of crustaceans and
cause severe economic losses to aquaculture. However, no commercial drugs presently …

The mechanisms that control the replication state, latency versus lytic, of human
herpesviruses have been under intense investigations. Here we summarize some of the …

An important step in the herpesvirus life cycle is the switch from latency to lytic reactivation.
The RTA transcription activator of Kaposi's sarcoma-associated herpesvirus (KSHV) acts as …

Kaposi's sarcoma-associated herpesvirus (KSHV) is a human gammaherpesvirus that has
been implicated in the pathogenesis of Kaposi's sarcoma and B-cell neoplasms. The …