Cancer systems biology and modeling: microscopic scale and multiscale approaches

A Masoudi-Nejad, G Bidkhori, SH Ashtiani… - Seminars in cancer …, 2015 - Elsevier
Cancer has become known as a complex and systematic disease on macroscopic,
mesoscopic and microscopic scales. Systems biology employs state-of-the-art …

Hybrid multiscale modeling and prediction of cancer cell behavior

MH Zangooei, J Habibi - PloS one, 2017 - journals.plos.org
Background Understanding cancer development crossing several spatial-temporal scales is
of great practical significance to better understand and treat cancers. It is difficult to tackle …

Stochastic cellular automata model of tumorous neurosphere growth: Roles of developmental maturity and cell death

GKH Zupanc, FB Zupanc, R Sipahi - Journal of theoretical biology, 2019 - Elsevier
The neurosphere assay is a powerful in vitro system for studying stem/progenitor-cell-driven
tissue growth. By employing a stochastic cellular automata model, we simulated the …

Simulation of Somatic Evolution Through the Introduction of Random Mutation to the Rules of Conway's Game of Life

MR King - Cellular and Molecular Bioengineering, 2024 - Springer
Abstract Introduction Conway's Game of Life (GOL), and related cellular automata (CA)
models, have served as interesting simulations of complex behaviors resulting from simple …

Modeling three-dimensional avascular tumor growth using lattice gas cellular automata

SMB Shrestha, G Joldes, A Wittek, K Miller - … Biomechanics for Medicine …, 2014 - Springer
We model and simulate avascular tumor growth in three dimensions using lattice gas
cellular automata (LGCA). Our 3D models are an advance over current state-of-the-art …

Computational simulation of blood flow and drug transportation in a large vasculature

C Coutey, M Berg, H Ho, P Hunter - Computational Biomechanics for …, 2016 - Springer
When the blood flow is considered as steady Poiseuille flow, the governing Navier–Stokes
equations can be reduced to the Hagen–Poiseuille law. This simplification results in a …

A computer simulation for 3d vasculature-based oxygen distribution and tumour growth

A Chapuis, H Ho - … Biomechanics for Medicine: New Approaches and …, 2015 - Springer
In this paper we present a three-dimensional (3D) tumourous cell growth model using a
hybrid cellular automata (CA) and continuum-based method. The CA model is employed to …

Intrinsic bifurcation and behavioural patterns in neuronal populations: A cellular automata-based approach

Y Zhang - International Journal of Knowledge-based and … - content.iospress.com
In this study, the objective is to model a neuronal population using cellular automata (CA)
rules that are both simple and realistic. Unlike in previous research, the primary aim is to …

Halting the hallmarks: a cellular automaton model of early cancer growth inhibition

J Butler, F Mackay, C Denniston, M Daley - Natural Computing, 2016 - Springer
Cancer treatment is a fragmented and varied process, as “cancer” is really hundreds of
different diseases. The “hallmarks of cancer” proposed by Hanahan and Weinberg (Cell 100 …

[图书][B] Using Cellular Automata and Lattice Boltzmann Methods to Model Cancer Growth: Analysis of Combination Treatment Outcomes

JL Butler - 2015 - search.proquest.com
In Canada it is estimated that 76,600 people will die of cancer in 2014. Cancer, a collection
of over 200 diseases, has differences existing between globally, between individuals and …