Cellular Ca 2+ homeostasis is maintained through the integrated and coordinated function
of Ca 2+ transport molecules, Ca 2+ buffers and sensors. These molecules are associated …

Cell-death and-survival decisions are critically controlled by intracellular Ca 2+ homeostasis
and dynamics at the level of the endoplasmic reticulum (ER). Inositol 1, 4, 5-trisphosphate …

Inositol 1, 4, 5-trisphosphate (IP3) receptors (IP3Rs) are tetrameric intracellular Ca2+-
release channels with each subunit containing a binding site for IP3 in the amino terminus …

Ca 2+ is a universal carrier of biological information: it controls cell life from its origin at
fertilization to its end in the process of programmed cell death. Ca 2+ is a conventional …

The endoplasmic reticulum (ER) and sarcoplasmic reticulum (SR) form major intracellular
Ca 2+ stores. Ryanodine receptors (RyRs) are large tetrameric ion channels in the SR and …

Inositol trisphosphate receptors (IP3Rs) are ubiquitous Ca2+-permeable channels that
mediate release of Ca2+ from the endoplasmic reticulum, thereby regulating numerous …

Abstract Inositol-1, 4, 5-trisphosphate receptors (InsP3Rs) and ryanodine receptors (RyRs)
are tetrameric intracellular Ca2+ channels. In each of these receptor families, the pore …

Abstract The inositol 1, 4, 5-trisphosphate (IP 3) receptor (IP 3 R) is a Ca 2+-release channel
mainly located in the endoplasmic reticulum (ER). Three IP 3 R isoforms are responsible for …

The role of intracellular Ca2+ signaling in starvation-induced autophagy remains unclear.
Here, we examined Ca2+ dynamics during starvation-induced autophagy and the …

Antiapoptotic Bcl-2-family members are well known for their 'mitochondrial'functions as
critical neutralizers of proapoptotic Bcl-2-family members, including the executioner …