Cardioprotective mechanisms of phytochemicals against doxorubicin-induced cardiotoxicity

AI Abushouk, A Ismail, AMA Salem, AM Afifi… - Biomedicine & …, 2017 - Elsevier
Doxorubicin (DOX) is an anthracycline antibiotic, which is effectively used in the treatment of
different malignancies, such as leukemias and lymphomas. Its most serious side effect is …

Cardio-oncology: mechanisms, drug combinations, and reverse cardio-oncology

Z Liang, Y He, X Hu - International Journal of Molecular Sciences, 2022 - mdpi.com
Chemotherapy, radiotherapy, targeted therapy, and immunotherapy have brought hope to
cancer patients. With the prolongation of survival of cancer patients and increased clinical …

Protective effect of Zingiber officinale roscoe against anticancer drug doxorubicin-induced acute nephrotoxicity

TA Ajith, MS Aswathy, U Hema - Food and chemical toxicology, 2008 - Elsevier
Oxidative stress due to abnormal production of reactive oxygen species has been implicated
in the nephrotoxicity induced by a commonly used anticancer antibiotic doxorubicin (DXN) …

Omega-3 fatty acids ameliorate doxorubicin-induced cardiorenal toxicity: In-vivo regulation of oxidative stress, apoptosis and renal Nox4, and in-vitro preservation of …

D Saleh, M Abdelbaset, A Hassan, O Sharaf… - Plos one, 2020 - journals.plos.org
This study examines the protective effects of omega‐3 fatty acids (OMG), a frequently used
nutritional therapy in cancer patients, against doxorubicin (DOX)‐induced acute cardiorenal …

[HTML][HTML] Combination of Nigella sativa with Glycyrrhiza glabra and Zingiber officinale augments their protective effects on doxorubicin-induced toxicity in h9c2 cells

A Hosseini, R Shafiee-Nick… - Iranian journal of basic …, 2014 - ncbi.nlm.nih.gov
Objective (s): The use of doxorubicin (DOX) is limited by its dose-dependent cardio toxicity in
which reactive Oxygen Species (ROS) play an important role in the pathological process …

The grape fruit flavonone naringin protects mice against doxorubicin-induced cardiotoxicity

GC Jagetia, TK Reddy - Journal of Molecular Biochemistry, 2014 - jmolbiochem.com
Doxorubicin (DOX), an anthracycline drug widely used for the treatment of various cancers,
causes a cumulative dose-dependent cardiac toxicity that is characterized by an irreversible …

Effect of Tinospora cordifolia-Derived Phytocomponents on Cancer: A Systematic Review

B Deepa, HV Babaji, JV Hosmani, AWH Alamir… - Applied Sciences, 2019 - mdpi.com
The major cancer therapeutic modalities include surgery, chemotherapy and radiotherapy.
Although these treatment regimens have played a significant role in effectively inhibiting …

Protective effect of saponins from Panax notoginseng against doxorubicin-induced cardiotoxicity in mice

L Liu, R Shi, Q Shi, Y Cheng, Y Huo - Planta medica, 2008 - thieme-connect.com
The dried rhizome of Panax notoginseng is a traditional Chinese herb extensively used for
treatment of cardiovascular diseases and other ailments. Panax notoginseng saponins …

[PDF][PDF] An indigenous plant bael (Aegle marmelos (L.) Correa) extract protects against the doxorubicin-induced cardiotoxicity in mice

GC Jagetia, P Venkatesh - Biochem physiol, 2015 - researchgate.net
Doxorubicin (DOX) is an effective antineoplastic agent widely used for the treatment of
various cancers; however, its clinical use is limited due the induction of dose-dependent …

Mechanism of the cardioprotective effects of docetaxel pre-administration against adriamycin-induced cardiotoxicity

M Tomonari, H To, M Nishida, T Mishima… - Journal of …, 2011 - Elsevier
We revealed that pre-treatment with docetaxel (DOC) 12 h before adriamycin (ADR)
administration significantly reduced ADR-induced toxic death compared with the …