Alignment-free sequence comparison: benefits, applications, and tools
Alignment-free sequence analyses have been applied to problems ranging from whole-
genome phylogeny to the classification of protein families, identification of horizontally …
genome phylogeny to the classification of protein families, identification of horizontally …
HaploGrep 2: mitochondrial haplogroup classification in the era of high-throughput sequencing
H Weissensteiner, D Pacher… - Nucleic acids …, 2016 - academic.oup.com
Mitochondrial DNA (mtDNA) profiles can be classified into phylogenetic clusters
(haplogroups), which is of great relevance for evolutionary, forensic and medical genetics …
(haplogroups), which is of great relevance for evolutionary, forensic and medical genetics …
Ancient genomes indicate population replacement in Early Neolithic Britain
The roles of migration, admixture and acculturation in the European transition to farming
have been debated for over 100 years. Genome-wide ancient DNA studies indicate …
have been debated for over 100 years. Genome-wide ancient DNA studies indicate …
[HTML][HTML] The genomic origins of the world's first farmers
The precise genetic origins of the first Neolithic farming populations in Europe and
Southwest Asia, as well as the processes and the timing of their differentiation, remain …
Southwest Asia, as well as the processes and the timing of their differentiation, remain …
Bioinformatics tools and databases to assess the pathogenicity of mitochondrial DNA variants in the field of next generation sequencing
C Bris, D Goudenege, V Desquiret-Dumas… - Frontiers in …, 2018 - frontiersin.org
The development of next generation sequencing (NGS) has greatly enhanced the diagnosis
of mitochondrial disorders, with a systematic analysis of the whole mitochondrial DNA …
of mitochondrial disorders, with a systematic analysis of the whole mitochondrial DNA …
Specifications of the ACMG/AMP standards and guidelines for mitochondrial DNA variant interpretation
EM McCormick, MT Lott, MC Dulik, L Shen… - Human …, 2020 - Wiley Online Library
Mitochondrial DNA (mtDNA) variant pathogenicity interpretation has special considerations
given unique features of the mtDNA genome, including maternal inheritance, variant …
given unique features of the mtDNA genome, including maternal inheritance, variant …
PhyloTree Build 17: Growing the human mitochondrial DNA tree
M Van Oven - Forensic Science International: Genetics Supplement …, 2015 - Elsevier
An accurate, up-to-date, detailed and global phylogenetic tree of human mitochondrial DNA
(mtDNA) is essential for various forensic mtDNA applications including data quality control …
(mtDNA) is essential for various forensic mtDNA applications including data quality control …
Ancient genomes from present-day France unveil 7,000 years of its demographic history
S Brunel, EA Bennett, L Cardin… - Proceedings of the …, 2020 - National Acad Sciences
Genomic studies conducted on ancient individuals across Europe have revealed how
migrations have contributed to its present genetic landscape, but the territory of present-day …
migrations have contributed to its present genetic landscape, but the territory of present-day …
A genomic Neolithic time transect of hunter-farmer admixture in central Poland
Ancient DNA genome-wide analyses of Neolithic individuals from central and southern
Europe indicate an overall population turnover pattern in which migrating farmers from …
Europe indicate an overall population turnover pattern in which migrating farmers from …
Sieve: Scalable in-situ dram-based accelerator designs for massively parallel k-mer matching
The rapid influx of biosequence data, coupled with the stagnation of the processing power of
modern computing systems, highlights the critical need for exploring high-performance …
modern computing systems, highlights the critical need for exploring high-performance …