Flattening the COVID-19 curve with natural killer cell based immunotherapies
M Market, L Angka, AB Martel, D Bastin… - Frontiers in …, 2020 - frontiersin.org
Natural Killer (NK) cells are innate immune responders critical for viral clearance and
immunomodulation. Despite their vital role in viral infection, the contribution of NK cells in …
immunomodulation. Despite their vital role in viral infection, the contribution of NK cells in …
Exhausted NK cells and cytokine storms in COVID-19: Whether NK cell therapy could be a therapeutic choice
M Ghasemzadeh, A Ghasemzadeh, E Hosseini - Human immunology, 2022 - Elsevier
The global outbreak of coronavirus-2019 (COVID-19) still claims more lives daily around the
world due to the lack of a definitive treatment and the rapid tendency of virus to mutate …
world due to the lack of a definitive treatment and the rapid tendency of virus to mutate …
[HTML][HTML] Early IFN-α signatures and persistent dysfunction are distinguishing features of NK cells in severe COVID-19
Longitudinal analyses of the innate immune system, including the earliest time points, are
essential to understand the immunopathogenesis and clinical course of coronavirus disease …
essential to understand the immunopathogenesis and clinical course of coronavirus disease …
Identification of druggable inhibitory immune checkpoints on Natural Killer cells in COVID-19
O Demaria, J Carvelli, L Batista, ML Thibult… - Cellular & molecular …, 2020 - nature.com
Infection with SARS-COV-2 is the cause of COVID-19 and has generated an unprecedented
health crisis worldwide. While most of the patients experience mild symptoms, around 20 …
health crisis worldwide. While most of the patients experience mild symptoms, around 20 …
How I treat and prevent COVID-19 in patients with hematologic malignancies and recipients of cellular therapies
F El Chaer, JJ Auletta… - Blood, The Journal of the …, 2022 - ashpublications.org
Patients with hematologic malignancies and recipients of hematopoietic cell transplantation
(HCT) are more likely to experience severe coronavirus disease 2019 (COVID-19) and have …
(HCT) are more likely to experience severe coronavirus disease 2019 (COVID-19) and have …
Single-cell transcriptomics reveal a unique memory-like NK cell subset that accumulates with ageing and correlates with disease severity in COVID-19
C Guo, M Wu, B Huang, R Zhao, L Jin, B Fu, P Wang… - Genome medicine, 2022 - Springer
Background Natural killer (NK) cells are innate lymphoid cells that mediate antitumour and
antiviral responses. However, very little is known about how ageing influences human NK …
antiviral responses. However, very little is known about how ageing influences human NK …
Population difference in allele frequency of HLA-C* 05 and its correlation with COVID-19 mortality
A Sakuraba, H Haider, T Sato - Viruses, 2020 - mdpi.com
Background: coronavirus disease 2019 (COVID-19) causes severe illness including
cytokine storms, but mortality among countries differs largely. In the present study, we …
cytokine storms, but mortality among countries differs largely. In the present study, we …
Harnessing memory NK cell to protect against COVID-19
S Soleimanian, R Yaghobi - Frontiers in pharmacology, 2020 - frontiersin.org
The worldwide struggle against the coronavirus disease 2019 (COVID-19) as a public health
crisis continues to sweep across the globe. Up to now, effective antiviral treatment against …
crisis continues to sweep across the globe. Up to now, effective antiviral treatment against …
Friends or foes? The knowns and unknowns of natural killer cell biology in COVID-19 and other coronaviruses in July 2020
C Manickam, S Sugawara, RK Reeves - PLoS pathogens, 2020 - journals.plos.org
The COVID-19 pandemic has caused more than 575,000 deaths worldwide as of mid-July
2020 and still continues globally unabated. Immune dysfunction and cytokine storm …
2020 and still continues globally unabated. Immune dysfunction and cytokine storm …
NK cell–derived IL-10 supports host survival during sepsis
IJ Jensen, PW McGonagill, NS Butler… - The Journal of …, 2021 - journals.aai.org
The dysregulated sepsis-induced cytokine storm evoked during systemic infection consists
of biphasic and interconnected pro-and anti-inflammatory responses. The contrasting …
of biphasic and interconnected pro-and anti-inflammatory responses. The contrasting …