Parkinson's disease is an increasingly prevalent and currently incurable neurodegenerative
disorder. At the molecular level, this disease is characterized by the formation of aberrant …

Alpha‐synuclein (ASYN) is a major constituent of the typical protein aggregates observed in
several neurodegenerative diseases that are collectively referred to as synucleinopathies. A …

One of the key molecular events underlying the pathogenesis of Parkinson's disease (PD) is
the aberrant misfolding and aggregation of the α-synuclein (αS) protein into higher-order …

The intrinsically disordered protein α-synuclein (αSN) is linked to Parkinson's Disease and
forms both oligomeric species and amyloid fibrils. The N-terminal part of monomeric αSN …

The human alpha‐Synuclein (αS) protein is of significant interest because of its association
with Parkinson's disease and related neurodegenerative disorders. The intrinsically …

Alpha-Synuclein (α-Syn) is a central protein in the pathogenesis of synucleinopathies, a
group of neurodegenerative disorders including Parkinson's disease (PD). Although its role …

In many human diseases, oligomeric species of amyloid proteins may play a pivotal role in
cytotoxicity. Many lines of evidence indicate that permeabilization of cellular membranes by …

α-synuclein, a presynaptic protein of poorly defined function, constitutes the main
component of Parkinson disease-associated Lewy bodies. Extensive biophysical …

α-Synuclein misfolding and aggregation is often accompanied by β-amyloid deposition in
some neurodegenerative diseases. We hypothesised that α-synuclein promotes β-amyloid …

Abstract α-Synuclein is a small presynaptic protein that is critically implicated in the onset of
Parkinson's disease and other neurodegenerative disorders. It has been assumed that the …