The etiology of endemic rickets was discovered a century ago. Vitamin D is the precursor of
25-hydroxyvitamin D and other metabolites, including 1, 25 (OH) 2D, the ligand for the …

Vitamin D deficiency is the most common nutritional deficiency, affecting almost one billion
people worldwide. Vitamin D is mostly known for its role in intestinal calcium absorption and …

1, 25-Dihydroxvitamin D3 [1, 25 (OH) 2D3] is the hormonally active form of vitamin D. The
genomic mechanism of 1, 25 (OH) 2D3 action involves the direct binding of the 1, 25 (OH) …

Importance Cohort studies have reported increased incidence of cardiovascular disease
(CVD) among individuals with low vitamin D status. To date, randomized clinical trials of …

The classical function of Vitamin D, which involves mineral balance and skeletal
maintenance, has been known for many years. With the discovery of vitamin D receptors in …

Vitamin D deficiency is associated with osteoporosis and is thought to increase the risk of
cancer and CVD. Despite these numerous potential health effects, data on vitamin D status …

Abstract Introduction: Adequate Vitamin D intake and its concentration in serum are
important for bone health and calcium–phosphate metabolism as well as for optimal function …

Introduction: Vitamin D has been primarily studied as an important factor influencing bone
and calcium metabolism. Metabolites of vitamin D are essential for whole-body calcium …

Chronic kidney disease (CKD) is a complex condition with a prevalence of 10–15%
worldwide. An inverse-graded relationship exists between cardiovascular events and …

Importance Low levels of vitamin D are associated with elevated blood pressure (BP) and
future cardiovascular events. Whether vitamin D supplementation reduces BP and which …