Engineering a biomimetic integrated scaffold for intervertebral disc replacement

L Du, Q Yang, J Zhang, M Zhu, X Ma, Y Zhang… - Materials Science and …, 2019 - Elsevier
Tissue engineering technology provides a promising alternative to restore physiological
functionality of damaged intervertebral disc (IVD). Advanced tissue engineering strategies …

New luminescence lifetime macro-imager based on a Tpx3Cam optical camera

R Sen, LM Hirvonen, A Zhdanov, P Svihra… - Biomedical Optics …, 2019 - opg.optica.org
The properties of a novel ultra-fast optical imager, Tpx3Cam, were investigated for
macroscopic wide-field phosphorescent lifetime imaging (PLIM) applications. The camera is …

Iodine nanoparticles enhance radiotherapy of intracerebral human glioma in mice and increase efficacy of chemotherapy

JF Hainfeld, SM Ridwan, Y Stanishevskiy, R Panchal… - Scientific Reports, 2019 - nature.com
Gliomas and other brain tumors have evaded durable therapies, ultimately causing about
20% of all cancer deaths. Tumors are widespread in the brain at time of diagnosis, limiting …

Intraurethral co-transplantation of bone marrow mesenchymal stem cells and muscle-derived cells improves the urethral closure

A Burdzinska, B Dybowski… - Stem Cell Research & …, 2018 - Springer
Background Cell therapy constitutes an attractive alternative to treat stress urinary
incontinence. Although promising results have been demonstrated in this field, the …

Quantitative impact of cell membrane fluorescence labeling on phagocytosis measurements in confrontation assays

Z Cseresnyes, MIA Hassan, HM Dahse… - Frontiers in …, 2020 - frontiersin.org
Phagocytosis is series of steps where the pathogens and the immune cells interact during
an invasion. This starts with the adhesion process between the host and pathogen cells, and …

Preliminary evaluation of safety and migration of immune activated mesenchymal stromal cells administered by subconjunctival injection for equine recurrent uveitis

JM Cassano, BC Leonard, BC Martins… - Frontiers in Veterinary …, 2023 - frontiersin.org
Introduction Equine recurrent uveitis (ERU), an immune mediated disease characterized by
repeated episodes of intra-ocular inflammation, affects 25% of horses in the USA and is the …

Limited accuracy of transurethral and periurethral intrasphincteric injections of cellular suspension

A Burdzinska, B Dybowski… - Neurourology and …, 2018 - Wiley Online Library
Aims The efficacy of cell therapy in patients with stress urinary incontinence (SUI) is lower
than expected. The aim of this study was to determine the injection accuracy rate both with …

Identification of the reporter gene combination that shows high contrast for cellular level MRI

N Hayashi, J Hata, T Yoshida, D Yoshimaru, Y Haga… - Plos one, 2024 - journals.plos.org
Currently, we can label the certain cells by transducing specific genes, called reporter
genes, and distinguish them from other cells. For example, fluorescent protein such as green …

Enhanced in vivo Optical Imaging of the Inflammatory Response to Acute Liver Injury in C57BL/6 Mice Using a Highly Bright Near‐Infrared BODIPY Dye

D Sirbu, S Luli, J Leslie, F Oakley… - ChemMedChem, 2019 - Wiley Online Library
Delving deeper is possible in whole‐body in vivo imaging using a super‐bright membrane‐
targeting BODIPY dye (BD). The dye was used to monitor homing of ex vivo fluorescently …

Extracellular ATP and macropinocytosis: their interactive and mutually supportive roles in cell growth, drug resistance, and EMT in cancer

M Evers, J Song, X Chen - Macropinocytosis: Functions and Mechanisms, 2022 - Springer
Macropinocytosis is one of the major mechanisms by which cancer cells uptake extracellular
nutrients from tumor microenvironment (TME) and plays very important roles in various steps …