Synthesis and characterization of Co (II), Ni (II), Cu (II) and Zn (II) chelates: DFT calculations, molecular docking and biological applications
An azo dye ligand,(Z)-2-(benzo [d] thiazol-2-yl)-2-(2-p-tolylhydrazono) acetonitrile (HL) and
its Co (II)(1), Cu (II)(2), Ni (II)(3) and Zn (II)(4) chelates were synthesized and considered …
its Co (II)(1), Cu (II)(2), Ni (II)(3) and Zn (II)(4) chelates were synthesized and considered …
Design, Synthesis and Biological Activities of (Thio) Urea Benzothiazole Derivatives
JE Mendieta-Wejebe, MC Rosales-Hernández… - International Journal of …, 2023 - mdpi.com
(Thio) ureas ((T) Us) and benzothiazoles (BTs) each have demonstrated to have a great
variety of biological activities. When these groups come together, the 2-(thio) …
variety of biological activities. When these groups come together, the 2-(thio) …
Structural, spectral, molecular docking, and molecular dynamics simulations of phenylthiophene-2-carboxylate compounds as potential anticancer agents
P Vennila, JS Al-Otaibi, G Venkatesh… - Polycyclic Aromatic …, 2024 - Taylor & Francis
Important biological compounds, namely, methyl 3-amino-4-(4-bromophenyl) thiophene-2-
carboxylate (BPTC) and methyl 3-amino-4-(4-chlorophenyl) thiophene-2-carboxylate …
carboxylate (BPTC) and methyl 3-amino-4-(4-chlorophenyl) thiophene-2-carboxylate …
Benzothiazole‐based apoptosis inducers: A comprehensive overview and future prospective
Cancer has become a major concern in healthcare globally, and over time, incidences and
prevalence of cancer are increasing. To counter this, a lot of anticancer drugs are approved …
prevalence of cancer are increasing. To counter this, a lot of anticancer drugs are approved …
New benzothiazole hybrids as potential VEGFR-2 inhibitors: design, synthesis, anticancer evaluation, and in silico study
A new series of 2-aminobenzothiazole hybrids linked to thiazolidine-2, 4-dione 4a–e, 1, 3, 4-
thiadiazole aryl urea 6a–d, and cyanothiouracil moieties 8a–d was synthesised. The in vitro …
thiadiazole aryl urea 6a–d, and cyanothiouracil moieties 8a–d was synthesised. The in vitro …
Liposomal formulations of a new zinc (II) complex exhibiting high therapeutic potential in a murine colon cancer model
N Ribeiro, M Albino, A Ferreira, C Escrevente… - International Journal of …, 2022 - mdpi.com
Colorectal cancer is the second leading cause of cancer-related mortality. Many current
therapies rely on chemotherapeutic agents with poor specificity for tumor cells. The clinical …
therapies rely on chemotherapeutic agents with poor specificity for tumor cells. The clinical …
Synthesis, biological evaluation, and in silico studies of indole‐tethered pyrazoline derivatives as anticancer agents targeting topoisomerase IIα
We herein report a new series of indole‐tethered pyrazoline derivatives as potent anticancer
agents. A total of 12 compounds were designed and synthesized by conventional as well as …
agents. A total of 12 compounds were designed and synthesized by conventional as well as …
Design, synthesis, biological evaluation, and in silico studies of 2‐aminobenzothiazole derivatives as potent PI3Kα inhibitors
A new series of 2‐aminobenzothiazole derivatives was designed, synthesized and
evaluated for their anticancer activity against the MCF7, MDAMB‐231, and HepG2 cancer …
evaluated for their anticancer activity against the MCF7, MDAMB‐231, and HepG2 cancer …
Solid-Phase Synthesis of 2-Benzothiazolyl and 2-(Aminophenyl) benzothiazolyl Amino Acids and Peptides
S Mourtas, V Athanasopoulos, D Gatos, K Barlos - Molecules, 2023 - mdpi.com
2-benzothiazoles and 2-(aminophenyl) benzothiazoles represent biologically interesting
heterocycles with high pharmacological activity. The combination of these heterocycles with …
heterocycles with high pharmacological activity. The combination of these heterocycles with …
Design, synthesis, biological assessment and molecular modeling studies of novel imidazothiazole-thiazolidinone hybrids as potential anticancer and anti …
A new series of imidazothiazole derivatives bearing thiazolidinone moiety (4a-g and 5a-d)
were designed, synthesized and evaluated for potential epidermal growth factor receptor …
were designed, synthesized and evaluated for potential epidermal growth factor receptor …