At early stages of carcinoma progression, epithelial cells undergo a program named
epithelial-to-mesenchymal transition characterized by the loss of the major component of the …

Several gastrointestinal phenotypes and impairment of duodenal mucosal barrier have been
reported in clinical studies in patients with functional dyspepsia (FD). Due to the preferential …

Innate immune cells in the tumor microenvironment have been proposed to control the
transition from benign to malignant stages. In many cancers, increased infiltration of natural …

Various strategies have been tested to identify serum biomarkers in patients with cancer.
Recently, the entire of proteins released by cultured tumor cells into the media, the so‐called …

Objective This study aimed at investigating whether a differential estrogen receptor beta (ER-
β) expression between the colonic subsites could correspond to a modification in …

Objective—To examine the expression and distribution of tight junction (TJ) and adherens
junction (AJ) proteins in canine duodenal and colonic mucosa. Sample—Mucosa obtained …

Background Familial adenomatous polyposis (FAP) is a disease characterized by the
development of hundreds to thousands of adenomatous polyps in the colorectum early in …

Familial adenomatous polyposis (FAP), caused by mutations in the Adenomatous Polyposis
Coli (APC) gene, is characterised by the early onset of hundreds to thousands of adenomas …

In this thesis mechanisms of ectodomain shedding of E-cadherin and cadherin-17, both
strongly expressed in the gut, were analyzed. In addition, the soluble forms of these …

Chapter One Inflammatory bowel disease (IBD) is characterized by chronic inflammation in
the gastrointestinal tract and represents an important risk factor for the onset of colorectal …