In adult mammals, massive sudden loss of cardiomyocytes after infarction overwhelms the
limited regenerative capacity of the myocardium, resulting in the formation of a collagen …

Peroxynitrite is a potent oxidant and nitrating species formed from the reaction between the
free radicals nitric oxide and superoxide. An excessive formation of peroxynitrite represents …

Mitochondria are indispensable for bioenergetics and for the regulation of physiological/
signaling events in cellular life. Although TNF-α-induced oxidative stress and mitochondrial …

Ischemic heart disease is a leading cause of death worldwide. After the onset of myocardial
infarction, many pathological changes take place and progress the disease towards heart …

The adult mammalian heart has limited endogenous regenerative capacity and heals
through the activation of inflammatory and fibrogenic cascades that ultimately result in the …

Objective: Accumulated evidence suggests that the primary cause of poor outcome after
subarachnoid hemorrhage is not only cerebral arterial narrowing but also early brain injury …

The myocardial extracellular matrix (ECM), which preserves the geometry and integrity of the
myocardium, is a dynamic structure whose component proteins are maintained by a finely …

Aims Remote ischemic conditioning (RIC) is considered a potential clinical approach to
reduce myocardial infarct size and ameliorate adverse post-infarct left ventricular (LV) …

BACKGROUND: Inflammatory pathways may promote extracellular matrix (ECM)
remodeling and chronic heart failure (CHF) progression. The relationship between markers …

Background Acute myocardial infarction (AMI) is followed by post AMI cardiac remodelling,
often leading to congestive heart failure. Homing of c‐kit+ endothelial progenitor cells (EPC) …