Microtubules are the backbone of all eukaryotic cells cytoskeleton. Their dynamic behaviour
constitutes the basis for many biological processes such as cellular motility, cytoplasmic …

Microtubules, highly dynamic components of the cytoskeleton, participate in diverse cellular
activities such as mitosis, cell migration, and intracellular trafficking. Dysregulation of …

Kinesin-1 is responsible for microtubule-based transport of numerous cellular cargoes.
Here, we explored the regulation of kinesin-1 by MAP7 proteins. We found that all four …

Microtubules (MTs) are key components of the eukaryotic cytoskeleton and are essential for
intracellular organization, organelle trafficking and mitosis. MT tasks depend on binding and …

Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (EGFR-TKIs) significantly
prolong the survival time of non-small-cell lung cancer (NSCLC) patients with EGFR …

Microtubules, tirelessly animated and highly dynamic structures, are vital for most cellular
processes and their intricacies are still being revealed even after a century since their …

Macroautophagy/autophagy, a fundamental process for degradation of macromolecules and
organelles, occurs constitutively at a basal level and is upregulated in response to stress …

Parkin, an E3 ubiquitin ligase well known for its role in the pathogenesis of juvenile
Parkinson disease, has been considered as a candidate tumor suppressor in certain types …

PTMs and microtubule-associated proteins (MAPs) are known to regulate microtubule
dynamicity in somatic cells. Reported literature on modulation of α-tubulin acetyl transferase …

Lung cancer is one of the most lethal cancers due to its highly metastatic spreading. The
motility of lung cancer cells is regulated by paracrine factors, such as TGF-β, in the tumor …