The human preterm brain is particularly susceptible to cerebral white matter injury (WMI) that
disrupts the normal progression of developmental myelination. Advances in the care of …

Prematurity, especially preterm birth (less than 32 weeks' gestation), is common and
associated with high rates of both survival and neurodevelopmental disability, especially …

Leukodystrophies are genetically determined disorders characterized by the selective
involvement of the central nervous system white matter. Onset may be at any age, from …

Human brain imaging has identified structural changes in gray and white matter that occur
with learning. However, ascribing imaging measures to underlying cellular and molecular …

Brain injury in premature infants is of enormous public health importance because of the
large number of such infants who survive with serious neurodevelopmental disability …

Formation of myelin, the electrical insulation on axons produced by oligodendrocytes, is
controlled by complex cell-cell signaling that regulates oligodendrocyte development and …

Objectives: The objectives of this review are to discuss the scope of neurologic injuries in
newborns with congenital heart disease, the mechanisms of injury, including prenatal, pre …

Objective: The major form of magnetic resonance imaging–defined white matter injury (WMI)
comprises diffuse lesions where the burden of small necrotic foci (microscopic necrosis) is …

During the second and third trimesters of human gestation, rapid neurodevelopment is
underpinned by fundamental processes including neuronal migration, cellular organization …

Oligodendrocytes and the myelin they produce are a remarkable vertebrate specialization
that enables rapid and efficient nerve conduction within the central nervous system. The …