Immunogenic cell death activates the tumor immune microenvironment to boost the immunotherapy efficiency
Z Li, X Lai, S Fu, L Ren, H Cai, H Zhang, Z Gu… - Advanced …, 2022 - Wiley Online Library
Tumor immunotherapy is only effective in a fraction of patients due to a low response rate
and severe side effects, and these challenges of immunotherapy in clinics can be addressed …
and severe side effects, and these challenges of immunotherapy in clinics can be addressed …
Ultrasound-targeted microbubble destruction remodels tumour microenvironment to improve immunotherapeutic effect
S Liu, Y Zhang, Y Liu, W Wang, S Gao, W Yuan… - British Journal of …, 2023 - nature.com
Cancer immunotherapy (CIT) has gained increasing attention and made promising progress
in recent years, especially immune checkpoint inhibitors such as antibodies blocking …
in recent years, especially immune checkpoint inhibitors such as antibodies blocking …
[HTML][HTML] Oxaliplatin and its derivatives–An overview
PD O'Dowd, DF Sutcliffe, DM Griffith - Coordination Chemistry Reviews, 2023 - Elsevier
Oxaliplatin was the third Pt-based anticancer drug to be clinically used worldwide. It exhibits
a broad spectrum of anticancer activity and was the first to be approved for the treatment of …
a broad spectrum of anticancer activity and was the first to be approved for the treatment of …
Nano ultrasound contrast agent for synergistic chemo‐photothermal therapy and enhanced immunotherapy against liver cancer and metastasis
Y Qiu, Z Wu, Y Chen, J Liao, Q Zhang… - Advanced …, 2023 - Wiley Online Library
Advanced liver cancer is the most fatal malignant cancer, and the clinical outcomes of
treatment are not very satisfactory due to the complexity and heterogeneity of the tumor …
treatment are not very satisfactory due to the complexity and heterogeneity of the tumor …
Engineering versatile nanomedicines for ultrasonic tumor immunotherapy
J Liang, X Qiao, L Qiu, H Xu, H Xiang, H Ding… - Advanced …, 2024 - Wiley Online Library
Due to the specific advantages of ultrasound (US) in therapeutic disease treatments, the
unique therapeutic US technology has emerged. In addition to featuring a low‐invasive …
unique therapeutic US technology has emerged. In addition to featuring a low‐invasive …
Targeted microbubbles for drug, gene, and cell delivery in therapy and immunotherapy
JA Navarro-Becerra, MA Borden - Pharmaceutics, 2023 - mdpi.com
Microbubbles are 1–10 μm diameter gas-filled acoustically-active particles, typically
stabilized by a phospholipid monolayer shell. Microbubbles can be engineered through …
stabilized by a phospholipid monolayer shell. Microbubbles can be engineered through …
Cardiac-targeted delivery of nuclear receptor RORα via ultrasound targeted microbubble destruction optimizes the benefits of regular dose of melatonin on sepsis …
S Wang, K Chen, Y Wang, Z Wang, Z Li… - Biomaterials …, 2023 - spj.science.org
Background Large-dose melatonin treatment in animal experiments was hardly translated
into humans, which may explain the dilemma that the protective effects against myocardial …
into humans, which may explain the dilemma that the protective effects against myocardial …
[HTML][HTML] Sono-processes: Emerging systems and their applicability within the (bio-) medical field
C Siebenmorgen, A Poortinga, P van Rijn - Ultrasonics sonochemistry, 2023 - Elsevier
Sonochemistry, although established in various fields, is still an emerging field finding new
effects of ultrasound on chemical systems and are of particular interest for the biomedical …
effects of ultrasound on chemical systems and are of particular interest for the biomedical …
[HTML][HTML] Ultrasound controllable release of proteolysis targeting chimeras for triple-negative breast cancer treatment
H He, F Li, R Tang, N Wu, Y Zhou, Y Cao… - Biomaterials …, 2024 - spj.science.org
Triple-negative breast cancer (TNBC) is a special subtype of breast cancer, which is highly
aggressive and incurable. Here, we proposed an ultrasound activatable bromodomain …
aggressive and incurable. Here, we proposed an ultrasound activatable bromodomain …
[HTML][HTML] Targeted nanobubbles of PD-L1 mAb combined with doxorubicin as a synergistic tumor repressor in hepatocarcinoma
Y Chen, X Luo, Y Liu, Y Zou, S Yang… - International Journal of …, 2022 - ncbi.nlm.nih.gov
Purpose Ultrasound nanobubbles (NBs) can kill tumor cells, mediated by their effects of
cavitation and acoustic perforation through ultrasound, while as novel drug carriers …
cavitation and acoustic perforation through ultrasound, while as novel drug carriers …