Introduction For the past two decades, microsatellite instability (MSI) has been reported as a
robust clinical biomarker associated with survival advantage attributed to its immunogenicity …

The aim of this study was to determine the clinical features, treatment factors, and prognosis
of patients with multiple primary malignant tumors (MPMTs). In total, 161 patients with …

Background Lynch syndrome is associated with the most common form of heritable bowel
cancer. There remains limited level 1 evidence on survival outcomes and rate of …

Incidence of Second Primary Malignancies Following Colorecta... : Medicine Incidence of Second
Primary Malignancies Following Colorectal Cancer: A Distinct Pattern of Occurrence Between …

Background Improvement in the prognosis of colorectal cancer (CRC) patients has led to
increasing occurrences of multiple primary malignancies (MPMs) alongside CRC but little is …

Abstract Background and Aim We evaluated the associations between gastric cancer (GC)
family history (FH) and colorectal cancer (CRC) risk and between CRC FH and GC/gastric …

Purpose The pattern of double primary cancers after treatment for gastric cancer is important
for a patient's survival. Materials and Methods We analyzed the clinicopathologic data of 214 …

A 42-year-old male patient was admitted to the Department of General Surgery of The First
Affiliated Hospital of Henan University of Science and Technology (Luoyang, China) …

Along with early-onset cancers, multiple primary cancers (MPCs) are likely resulting from
increased genetic susceptibility; however, the associated predisposition genes or …

Purpose The aim of the present study was to determine the profile of mismatch repair (MMR)
defects in Iranian colorectal cancer patients by using immunohistochemical staining for …