Bile acids are commonly known as digestive agents for lipids. The mechanisms of bile acids
in the gastrointestinal track during normal physiological conditions as well as hepatic and …

Bile acids (BA) are amphipathic steroid acids synthesized from cholesterol in the liver. They
act as detergents to expedite the digestion and absorption of dietary lipids and lipophilic …

To promote new thinking of the pathogenesis of Alzheimer's disease (AD), we examine the
central role of mitochondrial dysfunction in AD. Pathologically, AD is characterized by …

Alzheimer's disease (AD) is the most common cause of dementia worldwide and is
characterised pathologically by the accumulation of amyloid beta and tau protein …

This review will focus on how bile acids are being used in clinical trials to treat neurological
diseases due to their central involvement with the gut-liver-brain axis and their physiological …

The underlying pathophysiology of Parkinson's disease is complex, but mitochondrial
dysfunction has an established and prominent role. This is supported by an already large …

Neurological disorders (NDs) are characterized by progressive neuronal dysfunction
leading to synaptic failure, cognitive impairment, and motor injury. Among these diseases …

Mitochondria play a central role in a plethora of processes related to the maintenance of
cellular homeostasis and genomic integrity. They contribute to preserving the optimal …

Parkinson's disease (PD) is the second most common neurodegenerative illness majorly
affecting the population between the ages of 55 to 65 years. Progressive dopaminergic …

Mitochondrial dysfunction and oxidative stress are frequently observed in the early stages of
Alzheimer's disease (AD). Studies have shown that presenilin-1 (PS1), the catalytic subunit …