The interferon signature in autoimmune diseases

L Rönnblom, ML Eloranta - Current opinion in rheumatology, 2013 - journals.lww.com
The interferon signature in autoimmune diseases : Current Opinion in Rheumatology The
interferon signature in autoimmune diseases : Current Opinion in Rheumatology Log in or …

Cytokines as biomarkers in rheumatoid arthritis

A Burska, M Boissinot, F Ponchel - Mediators of inflammation, 2014 - Wiley Online Library
RA is a complex disease that develops as a series of events often referred to as disease
continuum. RA would benefit from novel biomarker development for diagnosis where new …

[HTML][HTML] TNF leads to mtDNA release and cGAS/STING-dependent interferon responses that support inflammatory arthritis

J Willemsen, MT Neuhoff, T Hoyler, E Noir, C Tessier… - Cell reports, 2021 - cell.com
Tumor necrosis factor (TNF) is a key driver of several inflammatory diseases, such as
rheumatoid arthritis, inflammatory bowel disease, and psoriasis, in which affected tissues …

The role of hypoxia in inflammatory disease

J Biddlestone, D Bandarra… - … journal of molecular …, 2015 - spandidos-publications.com
Mammals have developed evolutionarily conserved programs of transcriptional response to
hypoxia and inflammation. These stimuli commonly occur together in vivo and there is …

Association between type I interferon pathway activation and clinical outcomes in rheumatic and musculoskeletal diseases: a systematic literature review informing …

J Rodríguez-Carrio, A Burska, PG Conaghan… - RMD open, 2023 - rmdopen.bmj.com
Background Type I interferons (IFN-I) contribute to a broad range of rheumatic and
musculoskeletal diseases (RMDs). Compelling evidence suggests that the measurement of …

Anti-TNF therapy in spondyloarthritis and related diseases, impact on the immune system and prediction of treatment responses

S Menegatti, E Bianchi, L Rogge - Frontiers in immunology, 2019 - frontiersin.org
Immune-mediated inflammatory diseases (IMIDs), such as spondyloarthritis (SpA), psoriasis,
Crohn's disease (CD), and rheumatoid arthritis (RA) remain challenging illnesses. They …

Tumor necrosis factor-α inhibitor-related autoimmune disorders

L De Stefano, FB Pallavicini, E Mauric, V Piccin… - Autoimmunity …, 2023 - Elsevier
Biotechnological monoclonal antibodies and receptor antagonists capable of targeting
specific inflammatory actors, such as cytokines, cytokines receptors, co-stimulatory …

[HTML][HTML] Inflammatory bowel disease pathobiology: the role of the interferon signature

NP Andreou, E Legaki, M Gazouli - Annals of gastroenterology, 2020 - ncbi.nlm.nih.gov
The pathogenesis of inflammatory bowel disease (IBD) is still unclear, but includes both
inflammatory and autoimmune reactions. Current methodological approaches could better …

Genome‐wide association study of genetic predictors of anti–tumor necrosis factor treatment efficacy in rheumatoid arthritis identifies associations with polymorphisms …

D Plant, J Bowes, C Potter, KL Hyrich… - Arthritis & …, 2011 - Wiley Online Library
Objective Anti–tumor necrosis factor (anti‐TNF) agents are successful therapies in
rheumatoid arthritis (RA); however, inadequate response occurs in 30–40% of patients …

Relationship between the type I interferon signature and the response to rituximab in rheumatoid arthritis patients

RM Thurlings, M Boumans, J Tekstra… - Arthritis & …, 2010 - Wiley Online Library
Objective To analyze the relationship between the type I interferon (IFN) signature and
clinical response to rituximab in rheumatoid arthritis (RA) patients. Methods Twenty RA …