Thanks to its unique features at the nanoscale, nanofluidics, the study and application of
fluid flow in nanochannels/nanopores with at least one characteristic size smaller than 100 …

This Review addresses methods for obtaining sequence information directly from
unamplified genomic length DNA. Our generic starting point is a large piece of DNA that …

The power of nanofluidic channels to analyze DNA is described along with practical
experimental hints. As an introduction, a general overview is given on conventional DNA …

Nano-enabled technologies hold great promise for medicine and health. The rapid progress
by the physical sciences/engineering communities in synthesizing nanostructures and …

We report on the fabrication of nanofluidic channels directly buried in silicate glass with
transverse widths down to less than 50 nm using three-dimensional (3D) femtosecond laser …

DNA conformation in slitlike confinement is studied using Monte Carlo simulation and
scaling theory. We focus on analysing the in-plane DNA extension as a function of slit height …

We observed the free diffusion of individual 10 kbp,(1/2) λ (24.2 kbp), and λ (48.5 kbp)
double-stranded deoxyribonucleic acid (DNA) molecules in fused-silica nanoslits with …

Nanofluidic devices have typically explored a design space of patterns limited by a single
nanoscale structure depth. A method is presented here for fabricating nanofluidic structures …

Confining DNA molecules with high throughput and structural integrity is an important
challenge in nanochannel-based genomic mapping technology. Here we demonstrate …

Single‐molecule detection (SMD) allows static and dynamic heterogeneities from seemingly
equal molecules to be revealed in the studies of molecular structures and intra‐and inter …