The artificial pancreas (AP), known as closed-loop control of blood glucose in diabetes, is a
system combining a glucose sensor, a control algorithm, and an insulin infusion device. AP …

The control of diabetes is an interdisciplinary endeavor, which includes a significant
biomedical engineering component, with traditions of success beginning in the early 1960s …

Insulin treatment that mimics normal physiological patterns as closely as possible remains
the cardinal principle of treatment for type 1 diabetes. Since the last guidelines were …

Background Closed-loop systems link continuous glucose measurements to insulin delivery.
We aimed to establish whether closed-loop insulin delivery could control overnight blood …

Background: The level of continuous glucose monitoring (CGM) accuracy needed for insulin
dosing using sensor values (ie, the level of accuracy permitting non-adjunct CGM use) is a …

Background: This study evaluated the accuracy and performance of a fourth-generation
subcutaneous glucose sensor (Guardian™ Sensor 3) in the abdomen and arm. Methods …

Since the last guidelines were published in 2009 (1) the changes have been modest with
respect to insulin treatment, but the different modes have been refined especially when it …

Pursuit of a closed-loop artificial pancreas that automatically controls the blood glucose of
individuals with type 1 diabetes has intensified during the past 6years. Here we discuss the …

Background: In 2008–2009, the first multinational study was completed comparing closed-
loop control (artificial pancreas) to state-of-the-art open-loop therapy in adults with type 1 …

OBJECTIVE Nocturnal hypoglycemia can cause seizures and is a major impediment to tight
glycemic control, especially in young children with type 1 diabetes. We conducted an in …