Antifouling Strategies for Selective In Vitro and In Vivo Sensing

C Jiang, G Wang, R Hein, N Liu, X Luo… - Chemical …, 2020 - ACS Publications
The ability to fabricate sensory systems capable of highly selective operation in complex
fluid will undoubtedly underpin key future developments in healthcare. However, the …

Rational design of smart nano-platforms based on antifouling-nanomaterials toward multifunctional bioanalysis

M Mahmoudpour, A Jouyban, J Soleymani… - Advances in Colloid and …, 2022 - Elsevier
The ability to design nanoprobe devices with the capability of quantitative/qualitative
operation in complex media will probably underpin the main upcoming progress in …

[HTML][HTML] Sensitive immunosensing of α-synuclein protein in human plasma samples using gold nanoparticles conjugated with graphene: an innovative immuno …

ED Aminabad, A Mobed, M Hasanzadeh, MAH Feizi… - RSC …, 2022 - pubs.rsc.org
Parkinson's disease (PD) or simply Parkinson's is a long-term degenerative disorder of the
central nervous system, which mainly affects the motor system. Consequently, the detection …

[HTML][HTML] Alpha-synuclein in peripheral tissues as a possible marker for neurological diseases and other medical conditions

FJ Jiménez-Jiménez, H Alonso-Navarro… - Biomolecules, 2023 - mdpi.com
The possible usefulness of alpha-synuclein (aSyn) determinations in peripheral tissues
(blood cells, salivary gland biopsies, olfactory mucosa, digestive tract, skin) and in biological …

Biosensors for α-synuclein detection: Towards an improved diagnosis of Parkinson's disease

P Carneiro, S Morais, M do Carmo Pereira - TrAC Trends in Analytical …, 2023 - Elsevier
Diagnosis of Parkinson's disease remains a clinical exercise based on the assessment of
motor symptoms, which often results in diagnosis performed in more advanced stages of the …

[HTML][HTML] A systematic review and meta-analysis of alpha synuclein auto-antibodies in Parkinson's disease

KM Scott, A Kouli, SL Yeoh, MR Clatworthy… - Frontiers in …, 2018 - frontiersin.org
Immune dysfunction has been associated with Parkinson's disease (PD) and its progression.
Antibodies play an important role in both innate and adaptive responses, acting as powerful …

Immunochemical detection of α-synuclein autoantibodies in Parkinson's disease: correlation between plasma and cerebrospinal fluid levels

I Horvath, IA Iashchishyn, L Forsgren… - ACS chemical …, 2017 - ACS Publications
Autoantibodies to Parkinson's disease (PD) amyloidogenic protein, α-synuclein, were
recognized as a prospective biomarker for early disease diagnostics, yet there is …

The relevance of synuclein autoantibodies as a biomarker for Parkinson's disease

P Garg, F Maass, SM Sundaram, B Mollenhauer… - Molecular and Cellular …, 2022 - Elsevier
Several studies have investigated if the levels of α-synuclein autoantibodies (α-syn AAb)
differ in serum of Parkinson's disease (PD) patients and healthy subjects. Reproducible …

Electrochemical biosensors for the detection and study of α-synuclein related to Parkinson's disease–a review

Q Hassan, SP Li, C Ferrag, K Kerman - Analytica Chimica Acta, 2019 - Elsevier
Parkinson's disease (PD) is a long-term degenerative disorder that affects predominately
dopaminergic neurons in the substantia nigra, which mainly control movement. Alpha …

Functional molecular interfaces for impedance-based diagnostics

P Kanyong, AV Patil, JJ Davis - Annual Review of Analytical …, 2020 - annualreviews.org
In seeking to develop and optimize reagentless electroanalytical assays, a consideration of
the transducing interface features lies key to any subsequent sensitivity and selectivity. This …