Nociception is the process whereby primary afferent nerve fibers of the somatosensory
system detect noxious stimuli. Pungent irritants from pepper, mint, and mustard plants have …

Phosphoinositides (PIs) make up only a small fraction of cellular phospholipids, yet they
control almost all aspects of a cell's life and death. These lipids gained tremendous research …

The mammalian genome encodes 28 distinct members of the transient receptor potential
(TRP) superfamily of cation channels, which exhibit varying degrees of selectivity for …

The transient receptor potential (TRP) multigene superfamily encodes integral membrane
proteins that function as ion channels. Members of this family are conserved in yeast …

Transient receptor potential (TRP) channels are a large family of ion channel proteins,
surpassed in number in mammals only by voltage-gated potassium channels. TRP channels …

The 28 mammalian members of the super-family of transient receptor potential (TRP)
channels are cation channels, mostly permeable to both monovalent and divalent cations …

Seeing begins in the photoreceptors, where light is absorbed and signaled to the nervous
system. Throughout the animal kingdom, photoreceptors are diverse in design and purpose …

When we edited in 2007 the first issue on transient receptor potential channel in the
Handbook of Experimental Pharmacology, we were all very excited by the progress in this …

Elongation of Very Long chain fatty acids-4 (ELOVL4) protein is a member of the ELOVL
family of fatty acid elongases that is collectively responsible for catalyzing formation of long …

The mucolipin family of Transient Receptor Potential (TRPML) proteins is predicted to
encode ion channels expressed in intracellular endosomes and lysosomes. Loss-of-function …