Endocannabinoid modulation of nucleus accumbens microcircuitry and terminal dopamine release

DP Covey, AG Yocky - Frontiers in synaptic neuroscience, 2021 - frontiersin.org
The nucleus accumbens (NAc) is located in the ventromedial portion of the striatum and is
vital to valence-based predictions and motivated action. The neural architecture of the NAc …

Endogenous opiates and behavior: 2019

RJ Bodnar - Peptides, 2021 - Elsevier
This paper is the forty-second consecutive installment of the annual anthological review of
research concerning the endogenous opioid system, summarizing articles published during …

Ventral tegmental area glutamate neurons establish a mu-opioid receptor gated circuit to mesolimbic dopamine neurons and regulate opioid-seeking behavior

DJ McGovern, AM Polter, ED Prévost, A Ly… - …, 2023 - nature.com
A two-neuron model of ventral tegmental area (VTA) opioid function classically involves VTA
GABA neuron regulation of VTA dopamine neurons via a mu-opioid receptor dependent …

A ratiometric photoelectrochemical microsensor based on a small-molecule organic semiconductor for reliable in vivo analysis

Y Xiang, Y Kong, W Feng, X Ye, Z Liu - Chemical Science, 2021 - pubs.rsc.org
Photoelectrochemical (PEC) sensing has been developing quickly in recent years, while its
in vivo application is still in the infancy. The complexity of biological environments poses a …

Intermittent access to oxycodone decreases dopamine uptake in the nucleus accumbens core during abstinence

KR Samson, W Xu, S Kortagere… - Addiction biology, 2022 - Wiley Online Library
A major obstacle in treating opioid use disorder is the persistence of drug seeking or craving
during periods of abstinence, which is believed to contribute to relapse. Dopamine …

Brain opioid segments and striatal patterns of dopamine release induced by naloxone and morphine

E Shokri‐Kojori, M Naganawa… - Human Brain …, 2022 - Wiley Online Library
Opioid receptors are expressed throughout the brain and play a major role in regulating
striatal dopamine (DA) release. Clinical studies have shown that naloxone (NAL, a …

Stimuli predicting high-calorie reward increase dopamine release and drive approach to food in the absence of homeostatic need

A Gómez-A, TA Shnitko, KL Caref, SM Nicola… - Nutritional …, 2022 - Taylor & Francis
Animals and humans are motivated to consume high-fat, high-calorie foods by cues
predicting such foods. The neural mechanisms underlying this effect are not well …

Ivermectin increases striatal cholinergic activity to facilitate dopamine terminal function

HA Wadsworth, AMP Warnecke, JC Barlow… - Cell & Bioscience, 2024 - Springer
Ivermectin (IVM) is a commonly prescribed antiparasitic treatment with pharmacological
effects on invertebrate glutamate ion channels resulting in paralysis and death of …

[HTML][HTML] Herbal therapy in opioid withdrawal syndrome: A systematic review of randomized clinical trials

MH Nematollahi, MA Ahmadianmoghadam… - Addiction & …, 2022 - ncbi.nlm.nih.gov
Background: Medicinal plants have revealed much attention as an alternative or
complementary treatment for opioid withdrawal syndrome. The current review collects all …

Fast-scan voltammetry for in vivo measurements of neurochemical dynamics

CJ Meunier, LA Sombers - The brain reward system, 2021 - Springer
Background-subtracted fast-scan cyclic voltammetry (FSCV) is an electrochemical method
that enables the monitoring of neurochemical dynamics in brain tissue with sub-second …