Mast cells in the tumor microenvironment
A Aponte-López, S Muñoz-Cruz - … Microenvironment: Hematopoietic Cells …, 2020 - Springer
Mast cells are tissue-resident, innate immune cells that play a key role in the inflammatory
response and tissue homeostasis. Mast cells accumulate in the tumor stroma of different …
response and tissue homeostasis. Mast cells accumulate in the tumor stroma of different …
Mas-related G protein–coupled receptor X2 and its activators in dermatologic allergies
H Kühn, P Kolkhir, M Babina, M Düll… - Journal of Allergy and …, 2021 - Elsevier
The Mas-related G protein–coupled receptor X2 (MRGPRX2) is a multiligand receptor
responding to various exogenous and endogenous stimuli. Being highly expressed on skin …
responding to various exogenous and endogenous stimuli. Being highly expressed on skin …
Immunological outcomes of allergen-specific immunotherapy in food allergy
IgE-mediated food allergies are caused by adverse immunologic responses to food proteins.
Allergic reactions may present locally in different tissues such as skin, gastrointestinal and …
Allergic reactions may present locally in different tissues such as skin, gastrointestinal and …
Mast cells in diabetes and diabetic wound healing
J Dong, L Chen, Y Zhang, N Jayaswal, I Mezghani… - Advances in …, 2020 - Springer
Mast cells (MCs) are granulated, immune cells of the myeloid lineage that are present in
connective tissues. Apart from their classical role in allergies, MCs also mediate various …
connective tissues. Apart from their classical role in allergies, MCs also mediate various …
SCF and IL-33 regulate mouse mast cell phenotypic and functional plasticity supporting a pro-inflammatory microenvironment
R Molfetta, M Lecce, ND Milito, E Putro… - Cell Death & …, 2023 - nature.com
Mast cells (MCs) are multifaceted innate immune cells often present in the tumor
microenvironment (TME). Several recent findings support their contribution to the transition …
microenvironment (TME). Several recent findings support their contribution to the transition …
[HTML][HTML] Mast cells as protectors of health
Mast cells (MCs), which are well known for their effector functions in TH 2-skewed allergic
and also autoimmune inflammation, have become increasingly acknowledged for their role …
and also autoimmune inflammation, have become increasingly acknowledged for their role …
FcεR1-expressing nociceptors trigger allergic airway inflammation
T Crosson, JC Wang, B Doyle, H Merrison… - Journal of Allergy and …, 2021 - Elsevier
Background Lung nociceptor neurons amplify immune cell activity and mucus metaplasia in
response to an inhaled allergen challenge in sensitized mice. Objective We sought to …
response to an inhaled allergen challenge in sensitized mice. Objective We sought to …
Posterior corneoscleral limbus: Architecture, stem cells, and clinical implications
The limbus is a transition from the cornea to conjunctiva and sclera. In human eyes, this thin
strip has a rich variation of tissue structures and composition, typifying a change from scleral …
strip has a rich variation of tissue structures and composition, typifying a change from scleral …
The multifaceted roles of mast cells in immune homeostasis, infections and cancers
Mast cells (MCs) play important roles in normal immune responses and pathological states.
The location of MCs on the boundaries between tissues and the external environment …
The location of MCs on the boundaries between tissues and the external environment …
Cytokines stimulated by IL-33 in human skin mast cells: Involvement of NF-κB and p38 at distinct levels and potent co-operation with FcεRI and MRGPRX2
K Franke, Z Wang, T Zuberbier, M Babina - International Journal of …, 2021 - mdpi.com
The IL-1 family cytokine IL-33 activates and re-shapes mast cells (MCs), but whether and by
what mechanisms it elicits cytokines in MCs from human skin remains poorly understood …
what mechanisms it elicits cytokines in MCs from human skin remains poorly understood …