Deep hypothermic circulatory arrest in the pediatric population undergoing cardiac surgery with electroencephalography monitoring: a systematic review and meta …

AAAMM Alkhatip, MG Kamel, EM Farag… - … of Cardiothoracic and …, 2021 - Elsevier
Objective Cardiac surgery for repair of congenital heart defects poses unique hazards to the
developing brain. Deep hypothermic circulatory arrest (DHCA) is a simple and effective …

Perioperative electroencephalography in cardiac surgery with hypothermic circulatory arrest: a narrative review

WM McDevitt, T Gul, TJ Jones… - … and thoracic surgery, 2022 - academic.oup.com
OBJECTIVES Cardiac surgery with hypothermic circulatory arrest (HCA) is associated with
neurological morbidity of variable severity and electroencephalography (EEG) is a sensitive …

Low frequency power in cerebral blood flow is a biomarker of neurologic injury in the acute period after cardiac arrest

BR White, TS Ko, RW Morgan, WB Baker, EJ Benson… - Resuscitation, 2022 - Elsevier
Aim Cardiac arrest often results in severe neurologic injury. Improving care for these patients
is difficult as few noninvasive biomarkers exist that allow physicians to monitor neurologic …

Association of ongoing cerebral oxygen extraction during deep hypothermic circulatory arrest with postoperative brain injury

JM Lynch, CD Mavroudis, TS Ko, M Jacobwitz… - Seminars in thoracic and …, 2022 - Elsevier
Cardiac surgery utilizing circulatory arrest is most commonly performed under deep
hypothermia (∼ 18° C) to suppress tissue oxygen demand and provide neuroprotection …

Alterations in cerebral and cardiac mitochondrial function in a porcine model of acute carbon monoxide poisoning

DH Jang, S Piel, JC Greenwood, M Kelly… - Clinical …, 2021 - Taylor & Francis
Objectives The purpose of this study is the development of a porcine model of carbon
monoxide (CO) poisoning to investigate alterations in brain and heart mitochondrial function …

Carbon monoxide as a cellular protective agent in a swine model of cardiac arrest protocol

JC Greenwood, RW Morgan, BS Abella, FS Shofer… - Plos one, 2024 - journals.plos.org
Out-of-hospital cardiac arrest (OHCA) affects over 360,000 adults in the United States each
year with a 50–80% mortality prior to reaching medical care. Despite aggressive supportive …

Correlation of cerebral microdialysis with non-invasive diffuse optical cerebral hemodynamic monitoring during deep hypothermic cardiopulmonary bypass

TS Ko, CD Mavroudis, EJ Benson, RM Forti… - Metabolites, 2022 - mdpi.com
Neonates undergoing cardiac surgery involving aortic arch reconstruction are at an
increased risk for hypoxic-ischemic brain injury. Deep hypothermia is utilized to help …

Investigation of cerebral mitochondrial injury in a porcine survivor model of carbon monoxide poisoning

CD Mavroudis, A Lewis, JC Greenwood, M Kelly… - Journal of medical …, 2024 - Springer
Introduction Carbon monoxide (CO) is a colorless and odorless gas that is a leading cause
of environmental poisoning in the USA with substantial mortality and morbidity. The …

Are outcomes in congenital cardiac surgery better than ever?

RM Holcomb, A Ündar - Journal of Cardiac Surgery, 2022 - Wiley Online Library
Background and Aim of the Study Congenital heart disease is the most common congenital
defect among infants born in the United States. Within the first year of life, 1 in 4 of these …

Technology optimization for patient safety: a blockchain-based anesthesia record system architecture

R Orofino Giambastiani, R Sáenz, G Lahitte… - Frontiers in …, 2023 - frontiersin.org
Patient safety is acknowledged as a primary aim of anesthesiology. Anesthesia records
constitute the main document of the intraoperative course of anesthesia administration. In …