With the huge therapeutic potential, cancer immunotherapy is expected to become the
mainstream of cancer treatment. In the current field of cancer immunotherapy, there are …

β-lactam antibiotics are one of the most widely used and diverse classes of antimicrobial
agents for treating both Gram-negative and Gram-positive bacterial infections. The β-lactam …

CRISPR-Cas, as a tool for gene editing, has received extensive attention in recent years.
Anti-CRISPR (Acr) proteins can inactivate the CRISPR-Cas defense system during …

Sepsis is one of the deadliest disorders in the new century due to specific limitations in early
and differential diagnosis. Moreover, antimicrobial resistance (AMR) is becoming the …

Periodontal disease (PD) is an immune-inflammatory disease affecting the supporting
structures of the teeth, which results in progressive destruction of the hard and soft tissues …

The genus Limosilactobacillus (formerly Lactobacillus) contains multiple species considered
to be adapted to vertebrates, yet their genomic diversity has not been explored. In this study …

Background: The rise in antibiotic resistant bacteria poses a significant threat to public
health worldwide, necessitating innovative solutions. This study explores the role of …

CRISPR-Cas is an adaptive immunity system of prokaryotes, composed of CRISPR arrays
and the associated proteins. The successive addition of spacer sequences in the CRISPR …

ABSTRACT CRISPR Cas system is a revolutionary and precise genome editing system that
induces bacterial and archaeal adaptive immunity and already has shown several promising …

The clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-
associated protein 9 (Cas9) system is a powerful gene editing tool originated from …