The metabolic and molecular mechanisms of α-mangostin in cardiometabolic disorders
OD John, AT Mushunje… - International …, 2022 - spandidos-publications.com
α-mangostin is a xanthone predominantly encountered in Garcinia mangostana. Extensive
research has been carried out concerning the effects of this compound on various diseases …
research has been carried out concerning the effects of this compound on various diseases …
Bioactive compounds from mangosteen (Garcinia mangostana L.) as an antiviral agent via dual inhibitor mechanism against SARSCoV-2: an in silico approach
Severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) is the virus that causes
COVID-19 which is responsible for respiratory illness infection in humans. The virus was first …
COVID-19 which is responsible for respiratory illness infection in humans. The virus was first …
[HTML][HTML] A review on synthetic and pharmacological potential of compounds isolated from Garcinia mangostana Linn
SUP Saraswathy, LCP Lalitha, S Rahim, C Gopinath… - Phytomedicine Plus, 2022 - Elsevier
Abstract Background: The extracts of Garcinia mangostana (L) pericarp contain high
concentration of prenylated xanthones such as α-, β-and γ-mangostin and related …
concentration of prenylated xanthones such as α-, β-and γ-mangostin and related …
The Phytochemical α-Mangostin Inhibits Cervical Cancer Cell Proliferation and Tumor Growth by Downregulating E6/E7-HPV Oncogenes and KCNH1 Gene …
L Díaz, SV Bernadez-Vallejo, R Vargas-Castro… - International Journal of …, 2023 - mdpi.com
Cervical cancer is the fourth most common cancer among women worldwide. The main
factor associated with the onset and progression of this neoplasia is the human …
factor associated with the onset and progression of this neoplasia is the human …
Alpha-mangostin inhibits viral replication and suppresses nuclear factor kappa B (NF-κB)-mediated inflammation in dengue virus infection
M Tarasuk, P Songprakhon, T Chieochansin… - Scientific Reports, 2022 - nature.com
Severe dengue virus (DENV) infection results from viral replication and dysregulated host
immune response, which trigger massive cytokine production/cytokine storm. The result is …
immune response, which trigger massive cytokine production/cytokine storm. The result is …
[HTML][HTML] Identification of new benzofuran derivatives as STING agonists with broad-spectrum antiviral activity
A Paulis, A Onali, PO Vidalain, V Lotteau, C Jaquemin… - Virus Research, 2024 - Elsevier
Abstract The Stimulator of Interferon Genes (STING) is involved in cytosolic DNA sensing
and type I Interferons (IFN-I) induction. Aiming to identify new STING agonists with antiviral …
and type I Interferons (IFN-I) induction. Aiming to identify new STING agonists with antiviral …
Dual action effects of ethyl-p-methoxycinnamate against dengue virus infection and inflammation via NF-κB pathway suppression
M Tarasuk, P Songprakhon, P Muhamad, A Panya… - Scientific Reports, 2024 - nature.com
Dengue virus (DENV) infection can lead to severe outcomes through a virus-induced
cytokine storm, resulting in vascular leakage and inflammation. An effective treatment …
cytokine storm, resulting in vascular leakage and inflammation. An effective treatment …
Natural Compounds and Their Analogs as Antivirals Against Dengue Virus: A Review
AG Komarudin, A Adharis… - Phytotherapy …, 2024 - Wiley Online Library
Dengue virus (DENV) continues to pose a significant global health challenge, causing
diseases such as dengue fever, dengue hemorrhagic fever, and dengue shock syndrome …
diseases such as dengue fever, dengue hemorrhagic fever, and dengue shock syndrome …
Unlocking STING as a therapeutic antiviral strategy
A Paulis, E Tramontano - International Journal of Molecular Sciences, 2023 - mdpi.com
Invading pathogens have developed weapons that subvert physiological conditions to
weaken the host and permit the spread of infection. Cells, on their side, have thus developed …
weaken the host and permit the spread of infection. Cells, on their side, have thus developed …
Progress of cGAS-STING signaling pathway-based modulation of immune response by traditional Chinese medicine in clinical diseases
H Zhi, H Fu, Y Zhang, N Fan, C Zhao, Y Li… - Frontiers in …, 2024 - frontiersin.org
The cGAS-STING signaling pathway is a critical component of the innate immune response,
playing a significant role in various diseases. As a central element of this pathway, STING …
playing a significant role in various diseases. As a central element of this pathway, STING …