Acute kidney injury and distant organ dysfunction–network system analysis

R Matsuura, K Doi, H Rabb - Kidney international, 2023 - Elsevier
Acute kidney injury (AKI) occurs in about half of critically ill patients and is associated with
high in-hospital mortality, increased long-term mortality postdischarge, and subsequent …

Physiological network approach to prognosis in cirrhosis: A shifting paradigm

T Oyelade, KP Moore, AR Mani - Physiological Reports, 2024 - Wiley Online Library
Decompensated liver disease is complicated by multi‐organ failure and poor prognosis. The
prognosis of patients with liver failure often dictates clinical management. Current prognostic …

Health and disease are dynamic complex-adaptive states implications for practice and research

JP Sturmberg - Frontiers in psychiatry, 2021 - frontiersin.org
Interoception, the ability to convey one's overall physiological state, allows people to
describe their health along an experiential continuum, from excellent, very good, good, fair …

Brain biopsy for neurological diseases of unknown etiology in critically ill patients: Feasibility, safety, and diagnostic yield

B Mathon, M Favreau, V Degos, A Amelot… - Critical Care …, 2022 - journals.lww.com
OBJECTIVES: Brain biopsy is a useful surgical procedure in the management of patients
with suspected neoplastic lesions. Its role in neurologic diseases of unknown etiology …

Application of physiological network mapping in the prediction of survival in critically ill patients with acute liver failure

T Oyelade, KP Moore, AR Mani - Scientific Reports, 2024 - nature.com
Reduced functional connectivity of physiological systems is associated with poor prognosis
in critically ill patients. However, physiological network analysis is not commonly used in …

Pupillary dynamics predict long‐term outcome in a cohort of acute traumatic brain injury coma patients

E Monai, C Favaretto, A Salvalaggio… - Annals of Clinical …, 2023 - Wiley Online Library
Objective Examining the size and reactivity of the pupils of traumatic brain injury coma
patients is fundamental in the Neuro‐intensive care unit (ICU). Pupil parameters on …

Organ system network disruption is associated with poor prognosis in patients with chronic liver failure

YY Tan, S Montagnese, AR Mani - Frontiers in physiology, 2020 - frontiersin.org
Background A healthy individual has a high degree of functional connectivity between organ
systems, which can be represented graphically in a network map. Disruption of this system …

Acute kidney injury induces innate immune response and neutrophil activation in the lung

A Maeda, N Hayase, K Doi - Frontiers in Medicine, 2020 - frontiersin.org
Complication in acute kidney injury (AKI) is significantly associated with developing acute
respiratory failure (ARF), while ARF is one of the most important risks for AKI. These data …

Differential network testing reveals diverging dynamics of organ system interactions for survivors and non-survivors in intensive care medicine

R Schefzik, L Boland, B Hahn, T Kirschning… - Frontiers in …, 2022 - frontiersin.org
Statistical network analyses have become popular in many scientific disciplines, where an
important task is to test for differences between two networks. We describe an overall …

Network approach to prognosis in cirrhosis

T Oyelade - 2024 - discovery.ucl.ac.uk
Definitive treatment following decompensation of cirrhosis is limited to liver transplantation
based on prognosis. Although useful, current prognostic models do not consider the …