Marine natural products

JW Blunt, BR Copp, WP Hu, MHG Munro… - Natural product …, 2009 - pubs.rsc.org
Covering: 2007. Previous review: Nat. Prod. Rep., 2008, 25, 35This review covers the
literature published in 2007 for marine natural products, with 948 citations (627 for the …

Cytotoxic alkaloids derived from marine sponges: A comprehensive review

AM Elissawy, E Soleiman Dehkordi, N Mehdinezhad… - Biomolecules, 2021 - mdpi.com
Marine sponges (porifera) have proved to be a prolific source of unique bioactive secondary
metabolites, among which the alkaloids occupy a special place in terms of unprecedented …

Total Synthesis of the Tetracyclic Pyridinium Alkaloid epi‐Tetradehydrohalicyclamine B

AG Dalling, G Späth, A Fürstner - … Chemie International Edition, 2022 - Wiley Online Library
The first total synthesis of a tetracyclic marine pyridinium alkaloid hinged on recent
advances in chemoselectivity management: While many classical methods failed to afford …

The isolation of water-soluble natural products–challenges, strategies and perspectives

RGS Berlinck, CM Crnkovic, JR Gubiani… - Natural Product …, 2022 - pubs.rsc.org
Covering period: up to 2019 Water-soluble natural products constitute a relevant group of
secondary metabolites notably known for presenting potent biological activities. Examples …

A comprehensive review of marine sponge metabolites, with emphasis on Neopetrosia sp.

N Barzkar, S Sukhikh, O Babich - International Journal of Biological …, 2024 - Elsevier
The secondary metabolites that marine sponges create are essential to the advancement of
contemporary medicine and are often employed in clinical settings. Over the past five years …

Marine-derived lead fascaplysin: pharmacological activity, total synthesis, and structural modification

C Wang, S Wang, H Li, Y Hou, H Cao, H Hua, D Li - Marine Drugs, 2023 - mdpi.com
Fascaplysin is a planar structure pentacyclic alkaloid isolated from sponges, which can
effectively induce the apoptosis of cancer cells. In addition, fascaplysin has diverse …

A new organocatalytic desymmetrization reaction enables the enantioselective total synthesis of madangamine E

S Shiomi, BDA Shennan, K Yamazaki… - Journal of the …, 2022 - ACS Publications
The enantioselective total synthesis of madangamine E has been completed in 30 steps,
enabled by a new catalytic and highly enantioselective desymmetrizing intramolecular …

Marine-derived macrocyclic alkaloids (MDMAs): chemical and biological diversity

HI Althagbi, WM Alarif, KO Al-Footy, A Abdel-Lateff - Marine Drugs, 2020 - mdpi.com
The curiosity and attention that researchers have devoted to alkaloids are due to their
bioactivities, structural diversity, and intriguing chemistry. Marine-derived macrocyclic …

Unified total synthesis of madangamines A, C, and E

T Suto, Y Yanagita, Y Nagashima… - Journal of the …, 2017 - ACS Publications
A stereodivergent strategy for the synthesis of skipped dienes is developed. The method
consists of hydroboration of allenes and Migita–Kosugi–Stille coupling, which allows for …

Taxonomic and Functional Microbial Signatures of the Endemic Marine Sponge Arenosclera brasiliensis

AE Trindade-Silva, C Rua, GGZ Silva, BE Dutilh… - PLoS …, 2012 - journals.plos.org
The endemic marine sponge Arenosclera brasiliensis (Porifera, Demospongiae,
Haplosclerida) is a known source of secondary metabolites such as arenosclerins AC. In the …