Context: Isolated chondral and osteochondral defects of the knee are a difficult clinical
challenge, particularly in younger patients for whom alternatives such as partial or total knee …

Cartilage, especially articular cartilage, is a unique connective tissue consisting of
chondrocytes and cartilage matrix that covers the surface of joints. It plays a critical role in …

Background: The management of cartilage and osteochondral lesions in the knee remains
problematic and controversial. Our group reported the 2-year and 5-year results of a …

Background Autologous chondrocyte implantation (ACI) is an established and well-accepted
procedure for the treatment of localised full-thickness cartilage defects of the knee. Methods …

Articular cartilage has a limited capacity to repair following injury. Early intervention is
required to prevent progression of focal traumatic chondral and osteochondral defects to …

Background: Few comparative randomized long-term studies on microfracture versus
mosaicplasty have been published, and only 2 studies reported a follow-up of 10 years …

Clinical efforts to repair damaged articular cartilage (AC) currently face major obstacles due
to limited intrinsic repair capacity of the tissue and unsuccessful biological interventions …

Purpose To perform a systematic review of cartilage repair in athletes' knees to (1)
determine which (if any) of the most commonly implemented surgical techniques help …

Objective Autologous chondrocyte implantation (ACI) has not been proven to be durable
over the long-term. The purpose of this systematic review was (1) to evaluate activity level …

Purpose To compare long-term functional and radiological outcome following microfracture
technique (MF) versus osteochondral autologous transplantation (OAT) mosaicplasty for …