Reactive oxygen species (ROS) are critical for the progression of cardiovascular diseases,
inflammations and tumors. However, the mechanisms of how ROS sense metabolic stress …

The role of redox molecules, such as NO and ROS, as key mediators of immunity has
recently garnered renewed interest and appreciation. To regulate immune responses, these …

Background: Current paradigms suggest that nitric oxide (NO) produced by endothelial cells
(ECs) through endothelial nitric oxide synthase (eNOS) in the vessel wall is the primary …

The endothelial nitric oxide synthase (eNOS), the expression of which is regulated by a
range of transcriptional and posttranscriptional mechanisms, generates nitric oxide (NO) in …

Endothelial cells situated at the interface between blood and the vessel wall play a crucial
role in controlling vascular tone and homeostasis, particularly in determining the expression …

Uterine receptivity to implantation varies among species, and involves changes in
expression of genes that are coordinate with attachment of trophectoderm to uterine lumenal …

The endothelium is essential for the maintenance of vascular homeostasis. Central to this
role is the production of endothelium-derived nitric oxide (EDNO), synthesized by the …

Vascular endothelial cells are directly and continuously exposed to fluid shear stress
generated by blood flow. Shear stress regulates endothelial structure and function by …

Endothelial nitric oxide synthase (eNOS) plays an essential role in the regulation of
endothelial function and acts as a master regulator of vascular tone and homeostasis …

Nitric oxide (NO) is a short-lived gaseous signaling molecule. In blood vessels, it is
synthesized in a dynamic fashion by endothelial nitric oxide synthase (eNOS) and …