The prevalence of cardiovascular disease (CVD) is increasing over time. CVD is a
comorbidity in diabetes and contributes to premature death. Citrus flavonoids possess …

Doxorubicin is a widely used and promising anticancer drug; however, a severe dose-
dependent cardiotoxicity hampers its therapeutic value. Doxorubicin may cause acute and …

Hesperidin (Hsd) and its aglycone, hesperetin (Hst), are two flavonoids from citrus species
that have various biological properties, particularly those for the prevention of cancer and …

Breast cancer (BC) has high incidence and mortality rates, making it a major global health
issue. BC treatment has been challenging due to the presence of drug resistance and the …

The presented study was performed to verify whether rutin and/or quercetin can inhibit liver
injury induced by doxorubicin (DXR) in male Wistar rats. In this study, male Wistar rats were …

Carcinogenesis is a multistage process that involves a series of events comprising of
genetic and epigenetic changes leading to the initiation, promotion and progression of …

Doxorubicin (DOX) is an anthracycline antibiotic, which is effectively used in the treatment of
different malignancies, such as leukemias and lymphomas. Its most serious side effect is …

Background As an anthracycline antibiotic, doxorubicin (DOX) is one of the most potent and
widely used chemotherapeutic agents for various types of solid tumors. Unfortunately …

Flavonoids are secondary metabolites present in plant organs and tissues. These natural
metabolites are the most prevalent and display a wide range of beneficial physiological …

Ulcerative colitis is an idiopathic, chronic and relapsing inflammatory bowel disease, which
elicits the risk of colorectal cancer, the third most common malignancy in humans. It has …