[HTML][HTML] Immune reconstitution after allogeneic hematopoietic stem cell transplantation
J Ogonek, M Kralj Juric, S Ghimire… - Frontiers in …, 2016 - frontiersin.org
The timely reconstitution and regain of function of a donor-derived immune system is of
utmost importance for the recovery and long-term survival of patients after allogeneic …
utmost importance for the recovery and long-term survival of patients after allogeneic …
HSC niche biology and HSC expansion ex vivo
S Kumar, H Geiger - Trends in molecular medicine, 2017 - cell.com
Hematopoietic stem cell (HSC) transplantation can restore a new functional hematopoietic
system in recipients in cases where the system of the recipient is not functional or for …
system in recipients in cases where the system of the recipient is not functional or for …
[HTML][HTML] Cholinergic signals preserve haematopoietic stem cell quiescence during regenerative haematopoiesis
C Fielding, A García-García, C Korn… - Nature …, 2022 - nature.com
The sympathetic nervous system has been evolutionary selected to respond to stress and
activates haematopoietic stem cells via noradrenergic signals. However, the pathways …
activates haematopoietic stem cells via noradrenergic signals. However, the pathways …
[HTML][HTML] Sources of hematopoietic stem and progenitor cells and methods to optimize yields for clinical cell therapy
SR Panch, J Szymanski, BN Savani… - Biology of Blood and …, 2017 - Elsevier
Bone marrow (BM) aspirates, mobilized peripheral blood, and umbilical cord blood (UCB)
have developed as graft sources for hematopoietic stem and progenitor cells (HSPCs) for …
have developed as graft sources for hematopoietic stem and progenitor cells (HSPCs) for …
CD34+ cell dose effects on clinical outcomes after T‐cell replete haploidentical allogeneic hematopoietic stem cell transplantation for acute myeloid leukemia using …
Previous observations have reported controversial conclusions regarding cell dose and
survival endpoints after allogeneic hematopoietic stem cell transplantation (HSCT). We …
survival endpoints after allogeneic hematopoietic stem cell transplantation (HSCT). We …
[HTML][HTML] Infused total nucleated cell dose is a better predictor of transplant outcomes than CD34+ cell number in reduced-intensity mobilized peripheral blood …
PS Martin, S Li, S Nikiforow, EP Alyea III, JH Antin… - …, 2016 - ncbi.nlm.nih.gov
Mobilized peripheral blood is the most common graft source for allogeneic hematopoietic
stem cell transplantation following reduced-intensity conditioning. In assessing the effect of …
stem cell transplantation following reduced-intensity conditioning. In assessing the effect of …
Granulocyte colony-stimulating factor mobilizes dormant hematopoietic stem cells without proliferation in mice
JM Bernitz, MG Daniel, YS Fstkchyan… - Blood, The Journal of …, 2017 - ashpublications.org
Granulocyte colony-stimulating factor (G-CSF) is used clinically to treat leukopenia and to
enforce hematopoietic stem cell (HSC) mobilization to the peripheral blood (PB). However …
enforce hematopoietic stem cell (HSC) mobilization to the peripheral blood (PB). However …
Impact of infused CD34+ stem cell dosing for allogeneic peripheral blood stem cell transplantation with post-transplant cyclophosphamide
H Elmariah, SMH Naqvi, J Kim, T Nishihori… - Bone marrow …, 2021 - nature.com
Higher infused total nucleated cell dose (TNC) in allogeneic bone marrow transplant (BMT)
with post-transplant cyclophosphamide (PTCy) is associated with improved overall survival …
with post-transplant cyclophosphamide (PTCy) is associated with improved overall survival …
[HTML][HTML] Association of CD34 cell dose with 5-year overall survival after peripheral blood allogeneic hematopoietic cell transplantation in adults with hematologic …
TD Gauntner, CG Brunstein, Q Cao, D Weisdorf… - … and Cellular Therapy, 2022 - Elsevier
Higher CD34 cell dose is associated with improved engraftment after peripheral blood
allogeneic hematopoietic stem cell transplantation (alloHCT) but also may increase the risk …
allogeneic hematopoietic stem cell transplantation (alloHCT) but also may increase the risk …
[HTML][HTML] Small volume bone marrow aspirates with high progenitor cell concentrations maximize cell therapy dose manufacture and substantially reduce donor …
J Epah, G Spohn, K Preiß, MM Müller, J Dörr, R Bauer… - BMC medicine, 2023 - Springer
Background Bone marrow (BM) transplantation is a life-saving therapy for hematological
diseases, and the BM harbors also highly useful (progenitor) cell types for novel cell …
diseases, and the BM harbors also highly useful (progenitor) cell types for novel cell …