Eukaryotic cells possess an exquisitely interwoven and fine-tuned series of signal
transduction mechanisms with which to sense and respond to the ubiquitous fermentable …

The SNF1-related kinases are considered to be crucial elements of transcriptional,
metabolic and developmental regulation in response to stress. In yeast, SNF1 is one of the …

Background Most cells possess a sophisticated mechanism for sensing glucose and
responding to it appropriately. Glucose sensing and signaling in the budding yeast …

The yeast Saccharomyces cerevisiae senses glucose, its preferred carbon source, through
multiple signal transduction pathways. In one pathway, glucose represses the expression of …

In budding yeast, HXT genes encoding hexose permeases are induced by glucose via a
mechanism in which the F box protein Grr1 antagonizes activity of the transcriptional …

The yeast Saccharomyces cerevisiae employs different conserved signaling pathways to
adapt to altered availability of nutrient and energy sources. Crosstalk between the pathways …

The Snf1/AMP-activated protein kinase family has diverse roles in cellular responses to
metabolic stress. In Saccharomyces cerevisiae, Snf1 protein kinase has three isoforms of the …

In the yeast Saccharomyces cerevisiae, the Snf1 protein kinase of the Snf1/AMP-activated
protein kinase (AMPK) family regulates a wide range of responses to stress caused by …

Yeast cells respond to the quantity and quality of carbon and nitrogen sources in the
environment both by adjusting their transcriptional and metabolic profiles to make optimum …

Snf1 protein kinase regulates responses to glucose limitation and other stresses. Snf1
activation requires phosphorylation of its T-loop threonine by partially redundant upstream …