Heme in pathophysiology: a matter of scavenging, metabolism and trafficking across cell membranes
D Chiabrando, F Vinchi, V Fiorito, S Mercurio… - Frontiers in …, 2014 - frontiersin.org
Heme (iron-protoporphyrin IX) is an essential co-factor involved in multiple biological
processes: oxygen transport and storage, electron transfer, drug and steroid metabolism …
processes: oxygen transport and storage, electron transfer, drug and steroid metabolism …
Iron-deficiency in atopic diseases: innate immune priming by allergens and siderophores
F Roth-Walter - Frontiers in Allergy, 2022 - frontiersin.org
Although iron is one of the most abundant elements on earth, about a third of the world's
population are affected by iron deficiency. Main drivers of iron deficiency are beside the …
population are affected by iron deficiency. Main drivers of iron deficiency are beside the …
IL-22 controls iron-dependent nutritional immunity against systemic bacterial infections
Host immunity limits iron availability to pathogenic bacteria, but whether immunity limits
pathogenic bacteria from accessing host heme, the major source of iron in the body, remains …
pathogenic bacteria from accessing host heme, the major source of iron in the body, remains …
Flvcr1a deficiency promotes heme-based energy metabolism dysfunction in skeletal muscle
M Mistretta, V Fiorito, AL Allocco, G Ammirata, MY Hsu… - Cell Reports, 2024 - cell.com
The definition of cell metabolic profile is essential to ensure skeletal muscle fiber
heterogeneity and to achieve a proper equilibrium between the self-renewal and …
heterogeneity and to achieve a proper equilibrium between the self-renewal and …
Dietary hemoglobin rescues young piglets from severe iron deficiency anemia: Duodenal expression profile of genes involved in heme iron absorption
R Staroń, P Lipiński, M Lenartowicz, A Bednarz… - PLoS …, 2017 - journals.plos.org
Heme is an efficient source of iron in the diet, and heme preparations are used to prevent
and cure iron deficiency anemia in humans and animals. However, the molecular …
and cure iron deficiency anemia in humans and animals. However, the molecular …
Hemopexin counteracts systolic dysfunction induced by heme-driven oxidative stress
G Ingoglia, CM Sag, N Rex, L De Franceschi… - Free Radical Biology …, 2017 - Elsevier
Heart failure is a leading cause of morbidity and mortality in patients affected by different
disorders associated to intravascular hemolysis. The leading factor is the presence of …
disorders associated to intravascular hemolysis. The leading factor is the presence of …
Role of hemoglobin/heme scavenger protein hemopexin in atherosclerosis and inflammatory diseases
NU Mehta, ST Reddy - Current opinion in lipidology, 2015 - journals.lww.com
These studies suggest that heme scavenging is a major mechanism by which Hx defends
against oxidative stress and related inflammatory disorders. Hx therapy may provide a novel …
against oxidative stress and related inflammatory disorders. Hx therapy may provide a novel …
Crucial role of FLVCR1a in the maintenance of intestinal heme homeostasis
Aims: The maintenance of heme homeostasis, mucosa cell renewal, and redox environment
in the intestine is essential to permit digestion, absorption, cell proliferation, cell apoptosis …
in the intestine is essential to permit digestion, absorption, cell proliferation, cell apoptosis …
Hybrid magneto-fluorescent nano-probe for live apoptotic cells monitoring at brain cerebral ischemia
MM Mekawy, A Saito, A Sumiyoshi, JJ Riera… - Materials Science and …, 2019 - Elsevier
Abstract α-Fe 2 O 3 Magnetic nanoparticles (MNPs) have been synthesized, functionalized
at silica that ends up with-NH 2 group to form FMNPs. Conjugation of FMNPs with a …
at silica that ends up with-NH 2 group to form FMNPs. Conjugation of FMNPs with a …
[HTML][HTML] Data demonstrating the anti-oxidant role of hemopexin in the heart
G Ingoglia, CM Sag, N Rex, L De Franceschi, F Vinchi… - Data in brief, 2017 - Elsevier
The data presented in this article are related to the research article entitled Hemopexin
counteracts systolic dysfunction induced by heme-driven oxidative stress (G. Ingoglia, CM …
counteracts systolic dysfunction induced by heme-driven oxidative stress (G. Ingoglia, CM …