Heme (iron-protoporphyrin IX) is an essential co-factor involved in multiple biological
processes: oxygen transport and storage, electron transfer, drug and steroid metabolism …

Although iron is one of the most abundant elements on earth, about a third of the world's
population are affected by iron deficiency. Main drivers of iron deficiency are beside the …

Host immunity limits iron availability to pathogenic bacteria, but whether immunity limits
pathogenic bacteria from accessing host heme, the major source of iron in the body, remains …

The definition of cell metabolic profile is essential to ensure skeletal muscle fiber
heterogeneity and to achieve a proper equilibrium between the self-renewal and …

Heme is an efficient source of iron in the diet, and heme preparations are used to prevent
and cure iron deficiency anemia in humans and animals. However, the molecular …

Heart failure is a leading cause of morbidity and mortality in patients affected by different
disorders associated to intravascular hemolysis. The leading factor is the presence of …

These studies suggest that heme scavenging is a major mechanism by which Hx defends
against oxidative stress and related inflammatory disorders. Hx therapy may provide a novel …

Aims: The maintenance of heme homeostasis, mucosa cell renewal, and redox environment
in the intestine is essential to permit digestion, absorption, cell proliferation, cell apoptosis …

Abstract α-Fe 2 O 3 Magnetic nanoparticles (MNPs) have been synthesized, functionalized
at silica that ends up with-NH 2 group to form FMNPs. Conjugation of FMNPs with a …

The data presented in this article are related to the research article entitled Hemopexin
counteracts systolic dysfunction induced by heme-driven oxidative stress (G. Ingoglia, CM …